Researchers from Advanced Bio-Surfaces have developed test methods for evaluating the wear behavior of PEEK and CFR-PEEK against bone. Testing was performed with loads from 300-400 lbs at 37°C in 50% bovine serum using a custom built apparatus. Human femoral cadaver bone, synthetic delrin analogues, and a “BoneSim” analog were evaluated. The investigators concluded that BoneSim may provide a worst-case scenario for PEEK-on-bone testing of interpositional prostheses.