Efficient detection of eukaryotic calcium-sensing receptor

In direction of middle-up evaluation of polyclonal antibodies: subclass-specific N-glycosylation profiling of murine immunoglobulin G (IgG) by the use of HPLC-MS
- Lately, superior HPLC-MS methods based mostly on intact protein (“top-down”) or protein subunit (“middle-up/middle-down”) evaluation have been applied for the characterization of therapeutic monoclonal antibodies. Right here, we assess feasibility of middle-up/middle-down evaluation for polyclonal IgGs exhibiting in depth sequence variability. Particularly, we addressed IgGs from mouse, representing an essential mannequin system in immunological investigations.
- To acquire Fc/2 parts as conserved subunits of IgGs, we made use of the bacterial protease SpeB. For this function, we initially decided SpeB cleavage websites in murine IgGs. The ensuing Fc/2 parts attribute of various subclasses had been subsequently analysed by ion-pair reversed-phase HPLC hyphenated to high-resolution mass spectrometry. This enabled simultaneous relative quantification of IgG subclasses and their N-glycosylation variants, each of which affect IgG effector features.
- To evaluate methodology capabilities in an immunological context, we utilized the analytical workflow to polyclonal antibodies obtained from BALB/c mice immunized with the grass pollen allergen Phl p 6. The research revealed a shift in IgG subclasses and Fc-glycosylation patterns in whole and antigen-specific IgGs from totally different mouse cohorts, respectively. Finally, Fc/2 characterization might reveal different protein modifications together with oxidation, amino acid exchanges, and C-terminal lysine, and will thus be applied for high quality management of practical antibodies.
Environment friendly detection of eukaryotic calcium-sensing receptor (CaSR) by polyclonal antibody towards prokaryotic expressed truncated CaSR
Calcium-sensing receptor (CaSR), which is best identified for its motion as regulating calcium homeostasis, can bind varied ligands. To facilitate analysis on CaSR and perceive the receptor’s operate additional, an in silico designed truncated protein was developed. The ensuing protein folding indicated that 99% of predicted three dimensional (3D) construction residues are positioned in favored and allowed Ramachandran plots. Nonetheless, it was discovered that such protein doesn’t fold correctly when expressed in prokaryotic host cells.
Thioredoxin (Trx) tag was conjugated to extend the ultimate protein’s solubility, which may assist acquire the soluble antigen with higher immunogenic properties. The truncated recombinant proteins had been expressed and purified in two kinds (Trx-CaSR: RR19 and CaSR: RRJ19). The polyclonal antibody was induced by the rabbit immunization with the type of RR19. Western blot on mouse kidney lysates evidenced the correct immune recognition of the receptor by the produced antibody.
The specificity and sensitivity of antibodies had been additionally assayed by immunohistofluorescence. These experiments affirmed antibody’s means to point the receptor on the cell floor in native type and the potential for making use of such antibodies in additional mobile and tissue assays.

Doxorubicin (hydrochloride) |
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HY-15142 | MedChemExpress | 100mg | EUR 176.4 |
Doxorubicin hydrochloride |
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GA4969-100MG | Glentham Life Sciences | 100 mg | EUR 217.2 |
Doxorubicin hydrochloride |
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GA4969-10MG | Glentham Life Sciences | 10 mg | EUR 93.6 |
Doxorubicin hydrochloride |
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GA4969-25MG | Glentham Life Sciences | 25 mg | EUR 117.6 |
Doxorubicin hydrochloride |
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GA4969-50MG | Glentham Life Sciences | 50 mg | EUR 151.2 |
Doxorubicin hydrochloride |
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TNC00267 | ChemNorm | 20mg | Ask for price |
Doxorubicin hydrochloride USP |
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D005-10MG | TOKU-E | 10 mg | EUR 199.2 |
Doxorubicin hydrochloride USP |
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D005-25MG | TOKU-E | 25 mg | EUR 361.2 |
Doxorubicin Hydrochloride (Autophagy inducer) |
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SIH-390-10MG | Stressmarq | 10 mg | EUR 231.6 |
Description: The substance Doxorubicin Hydrochloride is a autophagy inducer. It is synthetically produced and has a purity of >98%. The pure substance is red solid which is soluble in water (50 mM).. |
Doxorubicin Hydrochloride (Autophagy inducer) |
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SIH-390-50MG | Stressmarq | 50 mg | EUR 634.8 |
Description: The substance Doxorubicin Hydrochloride is a autophagy inducer. It is synthetically produced and has a purity of >98%. The pure substance is red solid which is soluble in water (50 mM).. |
Erlotinib, Hydrochloride Salt |
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1588-100 | Biovision | EUR 202.8 |
Erlotinib, Hydrochloride Salt |
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1588-1000 | Biovision | EUR 477.6 |
Doxorubicin |
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A3966-10 | ApexBio | 10 mg | EUR 129.6 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
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A3966-100 | ApexBio | 100 mg | EUR 282 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
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A3966-25 | ApexBio | 25 mg | EUR 157.2 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
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A3966-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 157.2 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
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A3966-S | ApexBio | Evaluation Sample | EUR 97.2 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
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abx188695-1g | Abbexa | 1 g | EUR 560.4 |
Doxorubicin |
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D063-100MG | TOKU-E | 100 mg | EUR 1261.2 |
Doxorubicin |
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D063-25MG | TOKU-E | 25 mg | EUR 386.4 |
Doxorubicin |
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ADC-P-013 | Creative Biolabs | unit | Ask for price |
Doxorubicin |
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HY-15142A | MedChemExpress | 100mg | EUR 258 |
Erlotinib, Hydrochloride Salt, >99% |
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BC026-101 | GenDepot | 1g | EUR 327.6 |
Erlotinib, Hydrochloride Salt, >99% |
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BC026-102 | GenDepot | 2g | EUR 465.6 |
Erlotinib, Hydrochloride Salt, >99% |
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BC026-105 | GenDepot | 5g | EUR 684 |
17-DMAG, Hydrochloride Salt, >98% |
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BC024-001 | GenDepot | 1mg | EUR 213.6 |
17-DMAG, Hydrochloride Salt, >98% |
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BC024-005 | GenDepot | 5mg | EUR 343.2 |
17-DMAG, Hydrochloride Salt, >98% |
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BC024-010 | GenDepot | 10mg | EUR 489.6 |
17-DMAG, Hydrochloride Salt, >98% |
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BC024-025 | GenDepot | 25mg | Ask for price |
17-DMAG, Hydrochloride Salt, >99% |
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BC024-100 | GenDepot | 100mg | Ask for price |
17-DMAG, Hydrochloride Salt, >99% |
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BC024-101 | GenDepot | 1g | Ask for price |
17-DMAG, Hydrochloride Salt, >99% |
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BC024-250 | GenDepot | 250mg | Ask for price |
OSU-03012, Hydrochloride Salt, >98% |
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BC061-005 | GenDepot | 5mg | EUR 375.6 |
OSU-03012, Hydrochloride Salt, >98% |
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BC061-025 | GenDepot | 25mg | EUR 634.8 |
Doxorubicin HCl |
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20-abx184016 | Abbexa |
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Adriamycin (Doxorubicin) |
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E1KS1208 | EnoGene | 10mg | EUR 490.8 |
Doxorubicin 10mM |
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TG4120 | TopoGen | 0.25ml | EUR 187.2 |
Doxorubicin (Adriamycin) HCl |
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A1832-10 | ApexBio | 10 mg | EUR 150 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin (Adriamycin) HCl |
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A1832-100 | ApexBio | 100 mg | EUR 560.4 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin (Adriamycin) HCl |
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A1832-25 | ApexBio | 25 mg | EUR 226.8 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin (Adriamycin) HCl |
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A1832-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 135.6 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin HCl, 100mg |
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R2531-100mg | ACTGene | EUR 1560 |
Doxorubicin HCl, 10mg |
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R2531-10mg | ACTGene | EUR 236.4 |
Anti-EGFR-doxorubicin ADC |
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ADC-W-600 | Creative Biolabs | 1mg | Ask for price |
Description: This ADC product is comprised of an anti-EGFR monoclonal antibody conjugated via a linker to a doxorubicin |
Anti-CD22-DIBO-doxorubicin ADC |
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ADC-W-339 | Creative Biolabs | 1mg | Ask for price |
Description: This ADC product is comprised of an anti-CD22 monoclonal antibody conjugated via a DIBO linker to a doxorubicin |
PEGylated Liposomal Doxorubicin- 2 mg |
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PHPC002DX | ProFoldin | 2 mg | EUR 140.62 |
Description: This product includes 1 ml of liposomal doxorubicin at concentrations of 2 mg/ml doxorubicin and 16 mg/ml of lipids. |
PEGylated Liposomal Doxorubicin- 20 mg |
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PHPC020DX | ProFoldin | 20 mg | EUR 358.62 |
Description: This product includes 10 ml of liposomal doxorubicin at concentrations of 2 mg/ml doxorubicin and 16 mg/ml of lipids. |
Anti-TNFRSF8 (cAC10)-DIBO-doxorubicin ADC |
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ADC-W-406 | Creative Biolabs | 1mg | Ask for price |
Description: This ADC product is comprised of an anti-TNFRSF8 monoclonal antibody (cAC10) conjugated via a DIBO linker to a doxorubicin |
Anti-ERBB2 (Trastuzumab)-NGM-doxorubicin ADC |
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ADC-W-412 | Creative Biolabs | 1mg | Ask for price |
Description: This ADC product is comprised of an anti-ERBB2 monoclonal antibody conjugated via a NGM linker to adoxorubicin |
Anti-EGFR (cetuximab)-SMCC-Doxorubicin ADC |
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ADC-W-504 | Creative Biolabs | 1mg | Ask for price |
Description: This ADC product is comprised of an anti-EGFR monoclonal antibody (cetuximab) conjugated via a SMCC linker to Doxorubicin |
Anti-EpCAM (MOC31)-hydrazone-Doxorubicin ADC |
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ADC-W-581 | Creative Biolabs | 1mg | Ask for price |
Description: This ADC product is comprised of an anti-EPCAM monoclonal antibody (MOC31) conjugated via a hydrazone linker to Doxorubicin |
Anti-FUT3 (clone cBR96)-hydrazone-doxorubicin ADC |
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ADC-W-423 | Creative Biolabs | 1mg | Ask for price |
Description: This ADC product is comprised of an anti-FUT3 monoclonal antibody (clone cBR96) conjugated via a hydrazone linker to adoxorubicin |
Anti-CD70 (clone h1F6)-β-glucuronide-doxorubicin ADC |
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ADC-W-376 | Creative Biolabs | 1mg | Ask for price |
Description: This ADC product is comprised of an anti-CD70 monoclonal antibody (clone h1F6) conjugated via a β-glucuronide linker to a doxorubicin |
Bile salt |
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BB0225 | Bio Basic | 25g | EUR 95.5 |
Mannitol Salt |
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254027 | Scientific Laboratory Supplies | PK20 | EUR 13.68 |
Acriflavine Hydrochloride |
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A019-10G | TOKU-E | 10 g | EUR 66 |
Acriflavine Hydrochloride |
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A019-25G | TOKU-E | 25 g | EUR 94.8 |
Amodiaquine hydrochloride |
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A085-5G | TOKU-E | 5 g | EUR 66 |
TAME Hydrochloride |
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2050-100 | Biovision | EUR 151.2 |
TAME Hydrochloride |
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2050-1000 | Biovision | EUR 574.8 |
TAME Hydrochloride |
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2050-500 | Biovision | EUR 405.6 |
Amastatin . hydrochloride |
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10-016 | ProSci | 5 mg | EUR 440.88 |
Description: Slow, tight binding and competitive aminopeptidase (AP) inhibitor. Inhibits cytosolic leucine aminopeptidase, microsomal aminopeptidase M and bacterial leucine aminopeptidase, human serum aminopeptidase A (AP-A), aminopeptidase N (AP-N), tyrosine aminopeptidase, but not aminopeptidase B (AP-B). Amastatin is without effect on trypsin, papain, chymotrypsin, elastase, pepsin or thermolysin. Inhibits completely the Suc-Ala-Ala-Pro-Leu-pNA amidolytic enzyme. Slightly inhibits the formation of angiotensin III (Ang III) from Angiotensin II through AP-A, but significantly increases the potency of angiotensin III and [des-Asp1]-angiotensin I. Moderate inhibitor of mitochondrial intermediate peptidase (MIP). Weak inhibitor of simian immunodeficiency virus protease (SIV-PR). ANPEP (aminopeptidase N) is a host receptor targeted by porcine epidemic diarrhoea virus, human coronavirus 229E, feline coronavirus, canine coronavirus, transmissible gastroenteritis virus and infectious bronchitis virus. These viruses all belong to coronaviridae. ANPEP is therefore investigated as a potential target for SARS-CoV-2 infections. |
Irinotecan Hydrochloride |
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1752-250 | Biovision | EUR 464.4 |
Irinotecan Hydrochloride |
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1752-50 | Biovision | EUR 176.4 |
Epirubicin Hydrochloride |
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1753-25 | Biovision | EUR 548.4 |
Epirubicin Hydrochloride |
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1753-5 | Biovision | EUR 189.6 |
Gemcitabine Hydrochloride |
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1759-100 | Biovision | EUR 444 |
Gemcitabine Hydrochloride |
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1759-25 | Biovision | EUR 187.2 |
Amiodarone Hydrochloride |
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1828-100 | Biovision | EUR 151.2 |
Amiodarone Hydrochloride |
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1828-500 | Biovision | EUR 405.6 |
Phenformin hydrochloride |
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1889-100 | Biovision | EUR 138 |
Phenformin hydrochloride |
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1889-1000 | Biovision | EUR 430.8 |
Tomatidine hydrochloride |
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1893-25 | Biovision | EUR 164.4 |
Metformin, Hydrochloride |
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1691-5G | Biovision | EUR 189.6 |
EHNA hydrochloride |
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2265-25 | Biovision | EUR 339.6 |
EHNA hydrochloride |
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2265-5 | Biovision | EUR 138 |
Verapamil hydrochloride |
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2861-1G | Biovision | EUR 157.2 |
Verapamil hydrochloride |
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2861-5G | Biovision | EUR 392.4 |
Ticlopidine hydrochloride |
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2919-25 | Biovision | EUR 483.6 |
Ticlopidine hydrochloride |
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2919-5 | Biovision | EUR 183.6 |
SBE13 hydrochloride |
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2847-10 | Biovision | EUR 222 |
SBE13 hydrochloride |
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2847-50 | Biovision | EUR 705.6 |
AdipoRon hydrochloride |
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2572-25 | Biovision | EUR 705.6 |
AdipoRon hydrochloride |
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2572-5 | Biovision | EUR 222 |
Pargyline hydrochloride |
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2618-1000 | Biovision | EUR 210 |
Pargyline hydrochloride |
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2618-500 | Biovision | EUR 144 |
Clorgyline hydrochloride |
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2622-10 | Biovision | EUR 144 |
Clorgyline hydrochloride |
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2622-50 | Biovision | EUR 392.4 |
Clindamycin hydrochloride |
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2627-10 | Biovision | EUR 157.2 |
Clindamycin hydrochloride |
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2627-50 | Biovision | EUR 444 |
Loperamide hydrochloride |
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2683-1000 | Biovision | EUR 222 |
Loperamide hydrochloride |
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2683-500 | Biovision | EUR 157.2 |
Clonidine hydrochloride |
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2684-100 | Biovision | EUR 157.2 |
Clonidine hydrochloride |
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2684-500 | Biovision | EUR 430.8 |
Leelamine hydrochloride |
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2717-25 | Biovision | EUR 548.4 |
Leelamine hydrochloride |
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2717-5 | Biovision | EUR 183.6 |
Tetracycline Hydrochloride |
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A2517-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 129.6 |
Description: antibiotictoxicstore at -20°C, warm to room temperature before usesoluble in water at 10mg/mlsoluble in ethanol at 5mg/ml |
Tetracycline Hydrochloride |
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A2517-50 | ApexBio | 50 mg | EUR 157.2 |
Description: antibiotictoxicstore at -20°C, warm to room temperature before usesoluble in water at 10mg/mlsoluble in ethanol at 5mg/ml |
Alosetron Hydrochloride |
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A3159-10 | ApexBio | 10 mg | EUR 129.6 |
Description: Alosetron is s Serotonin 5HT3-receptor antagonist that is used in treatment of irritable bowel syndrome. |
Alosetron Hydrochloride |
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A3159-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 129.6 |
Description: Alosetron is s Serotonin 5HT3-receptor antagonist that is used in treatment of irritable bowel syndrome. |
Alosetron Hydrochloride |
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A3159-50 | ApexBio | 50 mg | EUR 268.8 |
Description: Alosetron is s Serotonin 5HT3-receptor antagonist that is used in treatment of irritable bowel syndrome. |
Asenapine hydrochloride |
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A3192-10 | ApexBio | 10 mg | EUR 166.8 |
Description: Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine shows high affinity (pKi) for numerous receptors. |
Asenapine hydrochloride |
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A3192-100 | ApexBio | 100 mg | EUR 514.8 |
Description: Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine shows high affinity (pKi) for numerous receptors. |
Asenapine hydrochloride |
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A3192-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 180 |
Description: Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine shows high affinity (pKi) for numerous receptors. |
Asenapine hydrochloride |
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A3192-50 | ApexBio | 50 mg | EUR 320.4 |
Description: Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine shows high affinity (pKi) for numerous receptors. |
AT7519 Hydrochloride |
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A3197-10 | ApexBio | 10 mg | EUR 223.2 |
Description: IC50: AT7519 showed potent antiproliferative activity (40-940 nmol/L) in a panel of human tumor cell lines.Cyclin-dependent kinases (CDK) play a central role in the growth, division, and death of eukaryotic cell. |
AT7519 Hydrochloride |
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A3197-100 | ApexBio | 100 mg | EUR 512.4 |
Description: IC50: AT7519 showed potent antiproliferative activity (40-940 nmol/L) in a panel of human tumor cell lines.Cyclin-dependent kinases (CDK) play a central role in the growth, division, and death of eukaryotic cell. |
AT7519 Hydrochloride |
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A3197-5 | ApexBio | 5 mg | EUR 166.8 |
Description: IC50: AT7519 showed potent antiproliferative activity (40-940 nmol/L) in a panel of human tumor cell lines.Cyclin-dependent kinases (CDK) play a central role in the growth, division, and death of eukaryotic cell. |
AT7519 Hydrochloride |
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A3197-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 180 |
Description: IC50: AT7519 showed potent antiproliferative activity (40-940 nmol/L) in a panel of human tumor cell lines.Cyclin-dependent kinases (CDK) play a central role in the growth, division, and death of eukaryotic cell. |
AT7519 Hydrochloride |
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A3197-50 | ApexBio | 50 mg | EUR 404.4 |
Description: IC50: AT7519 showed potent antiproliferative activity (40-940 nmol/L) in a panel of human tumor cell lines.Cyclin-dependent kinases (CDK) play a central role in the growth, division, and death of eukaryotic cell. |
Atrasentan hydrochloride |
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A3201-10 | ApexBio | 10 mg | EUR 710.4 |
Description: Description:IC50 Value: 0.0551 nM (for ET A receptor) [1]Atrasentan (A-147627) is an endothelin receptor antagonist being developed at Abbott Laboratories for the treatment of prostate cancer. |
Atrasentan hydrochloride |
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A3201-5 | ApexBio | 5 mg | EUR 451.2 |
Description: Description:IC50 Value: 0.0551 nM (for ET A receptor) [1]Atrasentan (A-147627) is an endothelin receptor antagonist being developed at Abbott Laboratories for the treatment of prostate cancer. |
Atrasentan hydrochloride |
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A3201-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 529.2 |
Description: Description:IC50 Value: 0.0551 nM (for ET A receptor) [1]Atrasentan (A-147627) is an endothelin receptor antagonist being developed at Abbott Laboratories for the treatment of prostate cancer. |
Atrasentan hydrochloride |
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A3201-50 | ApexBio | 50 mg | EUR 2025.6 |
Description: Description:IC50 Value: 0.0551 nM (for ET A receptor) [1]Atrasentan (A-147627) is an endothelin receptor antagonist being developed at Abbott Laboratories for the treatment of prostate cancer. |
BMS345541 hydrochloride |
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A3248-10 | ApexBio | 10 mg | EUR 282 |
Description: BMS-345541 is a highly selective inhibitor of IKK-1 and IKK-2 with IC50 values of 4?M and 0.3?M, respectively [1].BMS-345541 is a highly selective inhibitor of IKK that inhibits NF-?B-dependent transcription of pro-inflammatory cytokines both in vitro and in vivo. |
BMS345541 hydrochloride |
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A3248-5 | ApexBio | 5 mg | EUR 205.2 |
Description: BMS-345541 is a highly selective inhibitor of IKK-1 and IKK-2 with IC50 values of 4?M and 0.3?M, respectively [1].BMS-345541 is a highly selective inhibitor of IKK that inhibits NF-?B-dependent transcription of pro-inflammatory cytokines both in vitro and in vivo. |
BMS345541 hydrochloride |
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A3248-50 | ApexBio | 50 mg | EUR 714 |
Description: BMS-345541 is a highly selective inhibitor of IKK-1 and IKK-2 with IC50 values of 4?M and 0.3?M, respectively [1].BMS-345541 is a highly selective inhibitor of IKK that inhibits NF-?B-dependent transcription of pro-inflammatory cytokines both in vitro and in vivo. |
CCT241533 hydrochloride |
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A3292-1 | ApexBio | 1 mg | EUR 147.6 |
Description: CHK2 is a checkpoint kinase involved in the ATM-mediated response to double-strand DNA breaks. Inhibitors of CHK2 may increase the efficacy of genotoxic cancer therapies. CCT241533 has been identified and characterized as a novel CHK2 kinase inhibitor. |
CCT241533 hydrochloride |
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A3292-10 | ApexBio | 10 mg | EUR 528 |
Description: CHK2 is a checkpoint kinase involved in the ATM-mediated response to double-strand DNA breaks. Inhibitors of CHK2 may increase the efficacy of genotoxic cancer therapies. CCT241533 has been identified and characterized as a novel CHK2 kinase inhibitor. |
CCT241533 hydrochloride |
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A3292-5 | ApexBio | 5 mg | EUR 386.4 |
Description: CHK2 is a checkpoint kinase involved in the ATM-mediated response to double-strand DNA breaks. Inhibitors of CHK2 may increase the efficacy of genotoxic cancer therapies. CCT241533 has been identified and characterized as a novel CHK2 kinase inhibitor. |
Clemizole hydrochloride |
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A3316-10 | ApexBio | 10 mg | EUR 170.4 |
Description: IC50: 8 mM (NS4B) The NS4B protein is a key player in HCV replication. Disrupting NS4B function thus represents an attractive new anti-HCV strategy. |
Clemizole hydrochloride |
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A3316-100 | ApexBio | 100 mg | EUR 727.2 |
Description: IC50: 8 mM (NS4B) The NS4B protein is a key player in HCV replication. Disrupting NS4B function thus represents an attractive new anti-HCV strategy. |
Clemizole hydrochloride |
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A3316-5 | ApexBio | 5 mg | EUR 129.6 |
Description: IC50: 8 mM (NS4B) The NS4B protein is a key player in HCV replication. Disrupting NS4B function thus represents an attractive new anti-HCV strategy. |
Clemizole hydrochloride |
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A3316-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 142.8 |
Description: IC50: 8 mM (NS4B) The NS4B protein is a key player in HCV replication. Disrupting NS4B function thus represents an attractive new anti-HCV strategy. |
Clemizole hydrochloride |
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A3316-50 | ApexBio | 50 mg | EUR 477.6 |
Description: IC50: 8 mM (NS4B) The NS4B protein is a key player in HCV replication. Disrupting NS4B function thus represents an attractive new anti-HCV strategy. |
Elacridar hydrochloride |
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A3385-10 | ApexBio | 10 mg | EUR 224.4 |
Description: Elacridar is an inhibitor of breast cancer resistance protein (BCRP) and P-glycoprotein (P-GP) that has been used to improve the brain distribution of drugs. Recent studies have revealed that elacridar could probably be the substrate of these multidrug transporters (MDTs) [2]. |
Elacridar hydrochloride |
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A3385-100 | ApexBio | 100 mg | EUR 1015.2 |
Description: Elacridar is an inhibitor of breast cancer resistance protein (BCRP) and P-glycoprotein (P-GP) that has been used to improve the brain distribution of drugs. Recent studies have revealed that elacridar could probably be the substrate of these multidrug transporters (MDTs) [2]. |
Elacridar hydrochloride |
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A3385-50 | ApexBio | 50 mg | EUR 598.8 |
Description: Elacridar is an inhibitor of breast cancer resistance protein (BCRP) and P-glycoprotein (P-GP) that has been used to improve the brain distribution of drugs. Recent studies have revealed that elacridar could probably be the substrate of these multidrug transporters (MDTs) [2]. |
Etifoxine hydrochloride |
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A3401-10 | ApexBio | 10 mg | EUR 180 |
Description: Etifoxine is potentiator of GABAA receptor function in cultured neurons. Etifoxine preferentially acts on ?2 or ?3 subunit-containing GABAA receptors. Etifoxine exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. |
Etifoxine hydrochloride |
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A3401-50 | ApexBio | 50 mg | EUR 536.4 |
Description: Etifoxine is potentiator of GABAA receptor function in cultured neurons. Etifoxine preferentially acts on ?2 or ?3 subunit-containing GABAA receptors. Etifoxine exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. |
Gefitinib hydrochloride |
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A3433-100 | ApexBio | 100 mg | EUR 205.2 |
Description: The EGFR is a Mr 170,000 transmembrane glycoprotein with an external binding domain and an intracellular tyrosine kinase domain. Gefitinib (ZD-1839, Iressa) is an Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor. |
Gefitinib hydrochloride |
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A3433-250 | ApexBio | 250 mg | EUR 324 |
Description: The EGFR is a Mr 170,000 transmembrane glycoprotein with an external binding domain and an intracellular tyrosine kinase domain. Gefitinib (ZD-1839, Iressa) is an Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor. |
Guanfacine hydrochloride |
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A3451-10 | ApexBio | 10 mg | EUR 130.8 |
Description: Guanfacine, an anti-hypertensive agent, is a selective agonist of ?2A-adrenoceptor (?2AR) with a Kd value of 31 nM, displaying 60-fold selectivity over ?2B-adrenoceptors. |
Guanfacine hydrochloride |
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A3451-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 129.6 |
Description: Guanfacine, an anti-hypertensive agent, is a selective agonist of ?2A-adrenoceptor (?2AR) with a Kd value of 31 nM, displaying 60-fold selectivity over ?2B-adrenoceptors. |
Guanfacine hydrochloride |
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A3451-50 | ApexBio | 50 mg | EUR 315.6 |
Description: Guanfacine, an anti-hypertensive agent, is a selective agonist of ?2A-adrenoceptor (?2AR) with a Kd value of 31 nM, displaying 60-fold selectivity over ?2B-adrenoceptors. |
Hydroxyfasudil hydrochloride |
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A3479-10 | ApexBio | 10 mg | EUR 271.2 |
Description: Description:IC50 Value: 0.12 uM (ROCK1); 0.17 uM (ROCK2) [1]Hydroxyfasudil, metabolite of Fasudil, is a potent Rho-kinase inhibitor and vasodilator. |
Hydroxyfasudil hydrochloride |
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A3479-50 | ApexBio | 50 mg | EUR 703.2 |
Description: Description:IC50 Value: 0.12 uM (ROCK1); 0.17 uM (ROCK2) [1]Hydroxyfasudil, metabolite of Fasudil, is a potent Rho-kinase inhibitor and vasodilator. |
Icotinib Hydrochloride |
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A3482-10 | ApexBio | 10 mg | EUR 240 |
Description: Icotinib Hydrochloride is a potent and highly selective inhibitor of epidermal growth factor receptor tyrosine kinases (EGFR-TKI) with IC50 value of 5 nM. |
Icotinib Hydrochloride |
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A3482-5 | ApexBio | 5 mg | EUR 186 |
Description: Icotinib Hydrochloride is a potent and highly selective inhibitor of epidermal growth factor receptor tyrosine kinases (EGFR-TKI) with IC50 value of 5 nM. |
Icotinib Hydrochloride |
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A3482-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 199.2 |
Description: Icotinib Hydrochloride is a potent and highly selective inhibitor of epidermal growth factor receptor tyrosine kinases (EGFR-TKI) with IC50 value of 5 nM. |
Icotinib Hydrochloride |
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A3482-50 | ApexBio | 50 mg | EUR 584.4 |
Description: Icotinib Hydrochloride is a potent and highly selective inhibitor of epidermal growth factor receptor tyrosine kinases (EGFR-TKI) with IC50 value of 5 nM. |
Imatinib hydrochloride |
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A3487-100 | ApexBio | 100 mg | EUR 157.2 |
Description: Description:IC50 Value: 100 nM (PDGFR) [1]; 100 nM (c-Kit) [2]Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 ?M, 0.1 ?M and 0.1 ?M, respectively. |
Istaroxime hydrochloride |
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A3508-10 | ApexBio | 10 mg | EUR 564 |
Description: Istaroxime hydrochloride(PST2744) is a novel inhibitor of Na+/K+-ATPase with IC50 value of 0.43±0.15?M [1]. |
Istaroxime hydrochloride |
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A3508-100 | ApexBio | 100 mg | EUR 2203.2 |
Description: Istaroxime hydrochloride(PST2744) is a novel inhibitor of Na+/K+-ATPase with IC50 value of 0.43±0.15?M [1]. |
Istaroxime hydrochloride |
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A3508-2 | ApexBio | 2 mg | EUR 278.4 |
Description: Istaroxime hydrochloride(PST2744) is a novel inhibitor of Na+/K+-ATPase with IC50 value of 0.43±0.15?M [1]. |
Istaroxime hydrochloride |
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A3508-5 | ApexBio | 5 mg | EUR 390 |
Description: Istaroxime hydrochloride(PST2744) is a novel inhibitor of Na+/K+-ATPase with IC50 value of 0.43±0.15?M [1]. |
Istaroxime hydrochloride |
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A3508-50 | ApexBio | 50 mg | EUR 1476 |
Description: Istaroxime hydrochloride(PST2744) is a novel inhibitor of Na+/K+-ATPase with IC50 value of 0.43±0.15?M [1]. |
PJ34 hydrochloride |
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A4159-10 | ApexBio | 10 mg | EUR 142.8 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
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A4159-5 | ApexBio | 5 mg | EUR 129.6 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
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A4159-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 150 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
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A4159-50 | ApexBio | 50 mg | EUR 296.4 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
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A4159-S | ApexBio | Evaluation Sample | EUR 97.2 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
RETRA hydrochloride |
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A4485-10 | ApexBio | 10 mg | EUR 369.6 |
Description: IC50: Inhibit tumor cells growth with an IC50of about 4 M.Being defective for the tumor-suppressor function, mutant p53, a major contributor to malignancy, exerts oncogenic activity also by blocking another tumor-suppressing protein - p73. |
RETRA hydrochloride |
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A4485-50 | ApexBio | 50 mg | EUR 1363.2 |
Description: IC50: Inhibit tumor cells growth with an IC50of about 4 M.Being defective for the tumor-suppressor function, mutant p53, a major contributor to malignancy, exerts oncogenic activity also by blocking another tumor-suppressing protein - p73. |
Thiamine Hydrochloride |
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20-abx082137 | Abbexa |
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Vancomycin hydrochloride |
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20-abx082225 | Abbexa |
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Pyridoxine hydrochloride |
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abx082298-25g | Abbexa | 25 g | EUR 260.4 |
Thiamine Hydrochloride |
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20-abx082339 | Abbexa |
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Betaine Hydrochloride |
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abx082532-100g | Abbexa | 100 g | EUR 243.6 |
Vancomycin hydrochloride |
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20-abx082574 | Abbexa |
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Thiamine Hydrochloride |
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abx082609-25kg | Abbexa | 25 kg | EUR 6307.2 |
Erlotinib Hydrochloride |
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20-abx076664 | Abbexa |
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FTY720 Hydrochloride |
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20-abx076665 | Abbexa |
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Terazosin Hydrochloride |
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20-abx076677 | Abbexa |
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GSK690693 Hydrochloride |
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20-abx076782 | Abbexa |
|
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Amiodarone Hydrochloride |
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abx076829-1g | Abbexa | 1 g | EUR 326.4 |
Metformin Hydrochloride |
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abx076830-5g | Abbexa | 5 g | EUR 276 |
Bestatin hydrochloride |
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A8621-10 | ApexBio | 10 mg | EUR 157.2 |
Description: Bestatin hydrochloride, also known as Ubenimex, is an inhibitor of aminopeptidase B and N (APN)/CD13 [1].Bestatin, an antibiotic of microbial origin, is a potent inhibitor of some aminopeptidases which can be administered to cultured cells, intact animals and humans with low toxicity. |
Bestatin hydrochloride |
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A8621-100 | ApexBio | 100 mg | EUR 532.8 |
Description: Bestatin hydrochloride, also known as Ubenimex, is an inhibitor of aminopeptidase B and N (APN)/CD13 [1].Bestatin, an antibiotic of microbial origin, is a potent inhibitor of some aminopeptidases which can be administered to cultured cells, intact animals and humans with low toxicity. |
Bestatin hydrochloride |
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A8621-25 | ApexBio | 25 mg | EUR 226.8 |
Description: Bestatin hydrochloride, also known as Ubenimex, is an inhibitor of aminopeptidase B and N (APN)/CD13 [1].Bestatin, an antibiotic of microbial origin, is a potent inhibitor of some aminopeptidases which can be administered to cultured cells, intact animals and humans with low toxicity. |
Bestatin hydrochloride |
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A8621-5 | ApexBio | 5 mg | EUR 129.6 |
Description: Bestatin hydrochloride, also known as Ubenimex, is an inhibitor of aminopeptidase B and N (APN)/CD13 [1].Bestatin, an antibiotic of microbial origin, is a potent inhibitor of some aminopeptidases which can be administered to cultured cells, intact animals and humans with low toxicity. |
Flavopiridol hydrochloride |
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A8640-10 | ApexBio | 10 mg | EUR 129.6 |
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle. |
Flavopiridol hydrochloride |
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A8640-100 | ApexBio | 100 mg | EUR 528 |
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle. |
Flavopiridol hydrochloride |
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A8640-1000 | ApexBio | 1 g | EUR 3259.2 |
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle. |
Flavopiridol hydrochloride |
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A8640-25 | ApexBio | 25 mg | EUR 199.2 |
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle. |
Inhibitory Potential of Polyclonal Camel Antibodies towards New Delhi Metallo-β-lactamase-1 (NDM-1)
New Delhi Metallo-β-lactamase-1 (NDM-1) is probably the most prevalent kind of metallo-β-lactamase, in a position to hydrolyze virtually all antibiotics of the β-lactam group, resulting in multidrug-resistant micro organism. Up to now, there aren’t any clinically related inhibitors to combat NDM-1. Using dromedary polyclonal antibody inhibitors towards NDM-1 represents a promising new class of molecules with inhibitory exercise.
Within the present research, immunoreactivities of dromedary Immunoglobulin G (IgG) isotypes containing heavy-chain and standard antibodies had been examined after profitable immunization of dromedary utilizing growing quantities of the recombinant NDM-1 enzyme. Inhibition kinetic assays, carried out utilizing a spectrophotometric methodology with nitrocefin as a reporter substrate, demonstrated that IgG1, IgG2, and IgG3 had been in a position to inhibit not solely the hydrolytic exercise of NDM-1 but in addition Verona integron-encoded metallo-β-lactamase (VIM-1) (subclass B1) and L1 metallo-β-lactamase (L1) (subclass B3) with inhibitory focus (IC50) values starting from 100 to 0.04 μM.
Investigations on the flexibility of IgG subclasses to cut back the expansion of recombinant Escherichia coli BL21(DE3)/codon plus cells containing the recombinant plasmid expressing NDM-1, L1, or VIM-1 confirmed that the addition of IgGs (four and eight mg/L) to the cell tradition was unable to revive the susceptibility of carbapenems.
Apparently, IgGs had been in a position to work together with NDM-1, L1, and VIM-1 when examined on the periplasm extract of every cultured pressure. The inhibitory focus was within the micromolar vary for all β-lactams examined. A visualization of the 3D structural foundation utilizing the three enzyme Protein Knowledge Financial institution (PDB) recordsdata helps preliminarily the recorded inhibition of the three MBLs.
A Easy and Environment friendly Genetic Immunization Protocol for the Manufacturing of Extremely Particular Polyclonal and Monoclonal Antibodies towards the Native Type of Mammalian Proteins
We’ve got generated polyclonal and monoclonal antibodies by genetic immunization over the past twenty years. On this paper, we current our most profitable methodology acquired over these years and current the animals by which we obtained the very best charges of success. The method introduced is handy, simple, inexpensive, and generates antibodies towards mammalian proteins of their native type.
This protocol requires neither costly gear, resembling a gene gun, nor subtle methods such because the conjugation of gold microspheres, electroporation, or surgical procedure to inject in lymph nodes. The protocol introduced makes use of merely the purified plasmid expressing the protein of curiosity below a powerful promoter, which is injected at intramuscular and intradermal websites.
This method was examined in 5 species. Guinea pigs had been the animals of alternative for the manufacturing of polyclonal antibodies. Monoclonal antibodies could possibly be generated in mice by giving, as a final injection, a suspension of transfected cells. The antibodies detected their antigens of their native kinds. They had been extremely particular with very low non-specific background ranges, as assessed by immune-blots, immunocytochemistry, immunohistochemistry and circulation cytometry. We current herein an in depth and easy process to efficiently elevate particular antibodies towards native proteins.
Manufacturing of a polyclonal antibody towards inosine-uridine preferring nucleoside hydrolase of Acanthamoeba castellanii and its entry to prognosis of Acanthamoeba keratitis
Acanthamoeba keratitis (AK) is a uncommon illness however its prevalence all through the globe continues to develop, primarily as a result of elevated contact lens utilization. Since early-stage signs related to AK carefully resemble these from different corneal infections, correct prognosis is tough and this typically leads to delayed therapy and exacerbation of the illness, which might result in everlasting visible impairment. Accordingly, creating a speedy Acanthamoeba-specific diagnostic methodology is very desired.
Within the current research, a speedy and . Among the many huge portions of proteins secreted by the pathogenic Acanthamoeba, an open studying body of the inosine-uridine preferring nucleoside hyddifferential methodology for AK prognosis was developed utilizing the secretory proteins derived from the pathogenic Acanthamoebarolase (IPNH) gene was obtained. After expressing and purifying the IPNH protein utilizing the pGEX 4T-Three vector system, mice had been immunized with the purified proteins for polyclonal antibody technology.
Western blot was carried out utilizing protein lysates of the human corneal cell, non-pathogenic amoeba, pathogenic amoeba, and scientific amoeba isolate together with lysates from different causes of keratitis resembling Staphylococcus aureus, Pseudomonas aeruginosa, and Fusarium solani to verify Acanthamoeba-specificity.
Western blot utilizing the polyclonal IPNH antibody revealed that IPNH was Acanthamoeba-specific since these proteins had been solely noticed in lysates of Acanthamoeba origin or its tradition media. Our findings point out that the IPNH antibody of Acanthamoeba might function a possible agent for speedy and differential AK prognosis.
Aquaphile Coelenterazine h, lyophilized solid |
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9-10127 | Biotium |
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Description: Minimum order quantity: 1 unit of 50uG |
CF568 goat anti-mouse IgG(H+L) |
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9-20100 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF568 goat anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20101 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF568 goat anti-rabbit IgG(H+L) |
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9-20102 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF568 goat anti-rabbit IgG(H+L), highly cross-adsorbed |
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9-20103 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF568 goat anti-chicken IgY (IgG) (H+L), highly cross-adsorbed |
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9-20104 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF568 donkey anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20105 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF568 donkey anti-goat IgG(H+L), highly cross-adsorbed |
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9-20106 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF568 rabbit anti-goat IgG(H+L) |
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9-20107 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF568 goat anti-guinea pig IgG(H+L) |
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9-20108 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 goat anti-mouse IgG(H+L) |
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9-20110 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 goat anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20111 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 goat anti-rabbit IgG(H+L) |
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9-20112 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 goat anti-rabbit IgG(H+L), highly cross-adsorbed |
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9-20113 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 goat anti-chicken IgY (IgG) (H+L), highly cross-adsorbed |
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9-20114 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 donkey anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20115 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 donkey anti-goat IgG(H+L), highly cross-adsorbed |
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9-20116 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 rabbit anti-goat IgG(H+L) |
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9-20117 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 goat anti-guinea pig IgG(H+L) |
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9-20118 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 goat anti-mouse IgG(H+L) |
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9-20120 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 goat anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20121 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 goat anti-rabbit IgG(H+L) |
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9-20122 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 goat anti-rabbit IgG(H+L), highly cross-adsorbed |
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9-20123 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 donkey anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20124 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 donkey anti-rabbit IgG(H+L), highly cross-adsorbed |
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9-20125 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 goat anti-chicken IgY (IgG) (H+L), highly cross-adsorbed |
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9-20126 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 donkey anti-goat IgG(H+L), highly cross-adsorbed |
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9-20127 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 rabbit anti-goat IgG(H+L) |
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9-20128 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 goat anti-guinea pig IgG(H+L) |
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9-20129 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 goat anti-human IgG(H+L), highly cross-adsorbed |
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9-20132 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 goat anti-rat IgG(H+L), highly cross-adsorbed |
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9-20133 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 donkey anti-sheep IgG(H+L), highly cross-adsorbed |
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9-20134 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 rabbit anti-rat IgG(H+L), highly cross-adsorbed |
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9-20135 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 rabbit anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20136 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 donkey anti-rat IgG(H+L), highly cross-adsorbed |
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9-20137 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 goat anti-swine IgG(H+L) |
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9-20138 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF350 goat anti-mouse IgG(H+L) |
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9-20140 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF350 goat anti-rabbit IgG(H+L) |
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9-20141 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF350 donkey anti-goat IgG(H+L), highly cross-adsorbed |
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9-20142 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF350 goat anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20143 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF350 goat anti-rabbit IgG(H+L), highly cross-adsorbed |
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9-20144 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF350 goat anti-rat IgG(H+L), highly cross-adsorbed |
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9-20147 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF350 donkey anti-sheep IgG(H+L), highly cross-adsorbed |
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9-20148 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF350 rabbit anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20149 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 donkey anti-rabbit IgG(H+L), highly cross-adsorbed |
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9-20152 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 goat anti-human IgG(H+L), highly cross-adsorbed |
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9-20154 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 goat anti-rat IgG(H+L), highly cross-adsorbed |
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9-20155 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 donkey anti-sheep IgG(H+L), highly cross-adsorbed |
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9-20156 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 rabbit anti-rat IgG(H+L), highly cross-adsorbed |
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9-20157 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 rabbit anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20158 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 donkey anti-rat IgG(H+L), highly cross-adsorbed |
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9-20159 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 goat anti-swine IgG(H+L) |
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9-20160 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 rabbit anti-chicken IgY ( IgG) (H+L) |
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9-20164 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 rabbit anti-chicken IgY (IgG) (H+L) |
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9-20165 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF488A donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed |
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9-20166 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed |
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9-20167 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed |
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9-20168 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF488A donkey anti-guinea pig IgG(H+L), highly cross-adsorbed |
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9-20169 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 donkey anti-guinea pig IgG(H+L), highly cross-adsorbed |
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9-20170 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF633 donkey anti-guinea pig IgG(H+L), highly cross-adsorbed |
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9-20171 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF488A rabbit anti-sheep IgG(H+L), highly cross-adsorbed |
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9-20172 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 rabbit anti-sheep IgG(H+L), highly cross-adsorbed |
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9-20173 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF594 rabbit anti-sheep IgG(H+L), highly cross-adsorbed |
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9-20174 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF640R goat anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20175 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF640R goat anti-rabbit IgG(H+L), highly cross-adsorbed |
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9-20176 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF640R donkey anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20177 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF640R donkey anti-rabbit IgG(H+L), highly cross-adsorbed |
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9-20178 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF640R donkey anti-goat IgG(H+L), highly cross-adsorbed |
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9-20179 | Biotium |
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Description: Minimum order quantity: 1 unit of 1mg |
CF405M goat anti-mouse IgG(H+L) |
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9-20180 | Biotium |
|
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Description: Minimum order quantity: 1 unit of 1mg |
CF405M goat anti-rabbit IgG(H+L) |
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9-20181 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF405M goat anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20182 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
Biotin goat anti-mouse IgG(H+L) |
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9-20183 | Biotium |
|
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Description: Minimum order quantity: 1 unit of 1mg |
Biotin goat anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20184 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
Biotin goat anti-rabbit IgG(H+L) |
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9-20185 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
Biotin goat anti-rabbit IgG(H+L), highly cross-adsorbed |
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9-20186 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
Biotin donkey anti-goat IgG(H+L), highly cross-adsorbed |
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9-20189 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
Biotin donkey anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20190 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
Biotin donkey anti-rabbit IgG(H+L), highly cross-adsorbed |
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9-20191 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF640R goat anti-mouse IgG(H+L) |
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9-20197 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF350 goat anti-guinea pig IgG(H+L) |
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9-20198 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF640R donkey anti-rat IgG(H+L), highly cross-adsorbed |
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9-20199 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF640R rabbit anti-mouseIgG(H+L), highly cross-adsorbed |
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9-20200 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF640R rabbit anti-rat IgG(H+L), highly cross-adsorbed |
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9-20201 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF640R goat anti-rabbit IgG(H+L) |
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9-20202 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF488A chicken anti-mouse IgG(H+L) |
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9-20208 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF488A chicken anti-rabbit IgG(H+L) |
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9-20209 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF594 chicken anti-mouse IgG(H+L) |
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9-20221 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF633 chicken anti-mouse IgG(H+L) |
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9-20222 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF594 chicken anti-rabbit IgG(H+L) |
|||
9-20223 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF633 chicken anti-rabbit IgG(H+L) |
|||
9-20224 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF488A chicken anti-goat IgG(H+L) |
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9-20225 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF594 chicken anti-goat IgG(H+L) |
|||
9-20226 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF633 chicken anti-goat IgG(H+L) |
|||
9-20227 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF555 goat anti-human IgG(H+L), highly cross-adsorbed |
|||
9-20230 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF555 goat anti-mouse IgG(H+L), highly cross-adsorbed |
|||
9-20231 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF555 goat anti-rabbit IgG(H+L), highly cross-adsorbed |
|||
9-20232 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF555 goat anti-rat IgG(H+L), highly cross-adsorbed |
|||
9-20233 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF555 donkey anti-sheep IgG(H+L), highly cross-adsorbed |
|||
9-20234 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF555 rabbit anti-mouse IgG(H+L), highly cross-adsorbed |
|||
9-20235 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF555 goat anti-swine IgG(H+L) |
|||
9-20236 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF680 rabbit anti-guinea pig IgG(H+L) |
|||
9-20243 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF770 rabbit anti-guinea pig IgG(H+L) |
|||
9-20244 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF350 donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed |
|||
9-20275 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF555 donkey anti-guinea pig IgG (H+L), highly cross-adsorbed |
|||
9-20276 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF647 goat anti-human IgG(H+L), highly cross-adsorbed |
|||
9-20280 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF647 goat anti-mouse IgG(H+L), highly cross-adsorbed |
|||
9-20281 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF647 goat anti-rabbit IgG(H+L), highly cross-adsorbed |
|||
9-20282 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF647 goat anti-rat IgG(H+L), highly cross-adsorbed |
|||
9-20283 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF647 donkey anti-sheep IgG(H+L), highly cross-adsorbed |
|||
9-20284 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF647 rabbit anti-mouse IgG(H+L), highly cross-adsorbed |
|||
9-20285 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF647 goat anti-swine IgG(H+L) |
|||
9-20286 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF488A Bovine anti-goat IgG(H+L), highly cross-adsorbed |
|||
9-20293 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF568 Bovine anti-goat IgG(H+L), highly cross-adsorbed |
|||
9-20294 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF594 Bovine anti-goat IgG(H+L), highly cross-adsorbed |
|||
9-20295 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF633 Bovine anti-goat IgG(H+L), highly cross-adsorbed |
|||
9-20296 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF640R Bovine anti-goat IgG(H+L), highly cross-adsorbed |
|||
9-20297 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 Goat anti-mouse IgG (H+L), highly cross-adsorbed |
|||
9-20299 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 Goat anti-rabbit IgG (H+L), highly cross-adsorbed |
|||
9-20300 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF568 Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat) |
|||
9-20301 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF488A Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat) |
|||
9-20302 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF594 Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat) |
|||
9-20303 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF640R Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat) |
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9-20304 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 Donkey anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20305 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 goat anti-mouse IgG(H+L) |
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9-20306 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 Rabbit anti-mouse IgG(H+L), highly cross-adsorbed |
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9-20307 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 Donkey anti-rabbit IgG(H+L), highly cross-adsorbed |
|||
9-20308 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 goat anti-rabbit IgG(H+L) |
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9-20309 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed |
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9-20310 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 goat anti-chicken IgY(H+L), highly cross-adsorbed |
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9-20311 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 rabbit anti-chicken IgY (IgG) (H+L) |
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9-20312 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 Bovine anti-goat IgG(H+L), highly cross-adsorbed |
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9-20313 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 Donkey anti-goat IgG(H+L), highly cross-adsorbed |
|||
9-20314 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 rabbit anti-goat IgG(H+L) |
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9-20315 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 donkey anti-guinea pig IgG (H+L), highly cross-adsorbed |
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9-20316 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 goat anti-guinea pig IgG(H+L) |
|||
9-20317 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 donkey anti-human IgG(H+L), highly cross-adsorbed |
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9-20318 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 goat anti-human IgG(H+L), highly cross-adsorbed |
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9-20319 | Biotium |
|
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Description: Minimum order quantity: 1 unit of 1mg |
CF543 donkey anti-rat IgG(H+L), highly cross-adsorbed |
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9-20320 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 goat anti-rat IgG(H+L), highly cross-adsorbed |
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9-20321 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 donkey anti-sheep IgG(H+L), highly cross-adsorbed |
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9-20322 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 rabbit anti-sheep IgG(H+L), highly cross-adsorbed |
|||
9-20323 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 goat anti-swine IgG(H+L) |
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9-20324 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF543 Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat) |
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9-20328 | Biotium |
|
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Description: Minimum order quantity: 1 unit of 1mg |
CF350 Chicken Anti-Mouse IgG(H+L), 2 mg/mL |
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9-20331 | Biotium |
|
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Description: Minimum order quantity: 1 unit of 50uL |
CF350 Chicken Anti-Rabbit IgG(H+L), 2 mg/mL |
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9-20332 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF543 Chicken Anti-Goat IgG(H+L), 2 mg/mL |
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9-20333 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF543 Chicken Anti-Mouse IgG(H+L), 2 mg/mL |
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9-20334 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF543 Chicken Anti-Rabbit IgG(H+L), 2 mg/mL |
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9-20335 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF543 Rabbit Anit-Guinea Pig IgG(H+L), 2 mg/mL |
|||
9-20336 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF568 Chicken Anti-Goat IgG(H+L), 2 mg/mL |
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9-20337 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF568 Chicken Anti-Mouse IgG(H+L), 2 mg/mL |
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9-20338 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF568 Chicken Anti-Rabbit IgG(H+L), 2 mg/mL |
|||
9-20339 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF405M Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat), 2 mg/mL |
|||
9-20340 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF633 Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat), 2 mg/mL |
|||
9-20341 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF647 Goat Anti-Human IgM (mu chain), 2mg/mL |
|||
9-20346 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF488A Goat Anti-Human IgM (mu chain), 2mg/mL |
|||
9-20347 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF594 Goat Anti-Human IgM (mu chain), 2mg/mL |
|||
9-20348 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF640R Goat Anti-Human IgM (mu chain), 2mg/mL |
|||
9-20349 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |
CF350 Donkey anti-mouse IgG(H+L), highly cross-adsorbed |
|||
9-20350 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
CF350 Donkey anti-rabbit IgG(H+L), highly cross-adsorbed |
|||
9-20351 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 1mg |
R-phycoerythrin goat anti-mouse IgG(H+L), 0.5 mg/mL |
|||
9-20352 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 200uL |
R-phycoerythrin goat anti-rabbit IgG(H+L), 0.5 mg/mL |
|||
9-20353 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 200uL |
R-phycoerythrin goat anti-rat IgG(H+L), highly cross-adsorbed, 0.5 mg/mL |
|||
9-20354 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 200uL |
R-phycoerythrin goat anti-human IgG(H+L), highly cross-adsorbed, 0.5 mg/mL |
|||
9-20355 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 200uL |
CF405S Donkey anti-guinea pig IgG(H+L), highly cross-adsorbed, 2 mg/mL |
|||
9-20356 | Biotium |
|
|
Description: Minimum order quantity: 1 unit of 50uL |