Efficient detection of eukaryotic calcium-sensing receptor

In direction of middle-up evaluation of polyclonal antibodies: subclass-specific N-glycosylation profiling of murine immunoglobulin G (IgG) by the use of HPLC-MS
- Lately, superior HPLC-MS methods based mostly on intact protein (“top-down”) or protein subunit (“middle-up/middle-down”) evaluation have been applied for the characterization of therapeutic monoclonal antibodies. Right here, we assess feasibility of middle-up/middle-down evaluation for polyclonal IgGs exhibiting in depth sequence variability. Particularly, we addressed IgGs from mouse, representing an essential mannequin system in immunological investigations.
- To acquire Fc/2 parts as conserved subunits of IgGs, we made use of the bacterial protease SpeB. For this function, we initially decided SpeB cleavage websites in murine IgGs. The ensuing Fc/2 parts attribute of various subclasses had been subsequently analysed by ion-pair reversed-phase HPLC hyphenated to high-resolution mass spectrometry. This enabled simultaneous relative quantification of IgG subclasses and their N-glycosylation variants, each of which affect IgG effector features.
- To evaluate methodology capabilities in an immunological context, we utilized the analytical workflow to polyclonal antibodies obtained from BALB/c mice immunized with the grass pollen allergen Phl p 6. The research revealed a shift in IgG subclasses and Fc-glycosylation patterns in whole and antigen-specific IgGs from totally different mouse cohorts, respectively. Finally, Fc/2 characterization might reveal different protein modifications together with oxidation, amino acid exchanges, and C-terminal lysine, and will thus be applied for high quality management of practical antibodies.
Environment friendly detection of eukaryotic calcium-sensing receptor (CaSR) by polyclonal antibody towards prokaryotic expressed truncated CaSR
Calcium-sensing receptor (CaSR), which is best identified for its motion as regulating calcium homeostasis, can bind varied ligands. To facilitate analysis on CaSR and perceive the receptor’s operate additional, an in silico designed truncated protein was developed. The ensuing protein folding indicated that 99% of predicted three dimensional (3D) construction residues are positioned in favored and allowed Ramachandran plots. Nonetheless, it was discovered that such protein doesn’t fold correctly when expressed in prokaryotic host cells.
Thioredoxin (Trx) tag was conjugated to extend the ultimate protein’s solubility, which may assist acquire the soluble antigen with higher immunogenic properties. The truncated recombinant proteins had been expressed and purified in two kinds (Trx-CaSR: RR19 and CaSR: RRJ19). The polyclonal antibody was induced by the rabbit immunization with the type of RR19. Western blot on mouse kidney lysates evidenced the correct immune recognition of the receptor by the produced antibody.
The specificity and sensitivity of antibodies had been additionally assayed by immunohistofluorescence. These experiments affirmed antibody’s means to point the receptor on the cell floor in native type and the potential for making use of such antibodies in additional mobile and tissue assays.

Doxorubicin hydrochloride |
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GA4969-100MG | Glentham Life Sciences | 100 mg | EUR 217.2 |
Doxorubicin hydrochloride |
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GA4969-10MG | Glentham Life Sciences | 10 mg | EUR 93.6 |
Doxorubicin hydrochloride |
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GA4969-25MG | Glentham Life Sciences | 25 mg | EUR 117.6 |
Doxorubicin hydrochloride |
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GA4969-50MG | Glentham Life Sciences | 50 mg | EUR 151.2 |
Doxorubicin (hydrochloride) |
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HY-15142 | MedChemExpress | 100mg | EUR 176.4 |
Doxorubicin hydrochloride |
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TNC00267 | ChemNorm | 20mg | Ask for price |
Doxorubicin hydrochloride, 98% |
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GP9056-100 | Glentham Life Sciences | 100 | EUR 140.2 |
Doxorubicin hydrochloride, 98% |
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GP9056-25 | Glentham Life Sciences | 25 | EUR 56.1 |
Doxorubicin hydrochloride USP |
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D005-10MG | TOKU-E | 10 mg | EUR 199.2 |
Doxorubicin hydrochloride USP |
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D005-25MG | TOKU-E | 25 mg | EUR 361.2 |
Doxorubicin hydrochloride, USP grade |
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GA4969-10 | Glentham Life Sciences | 10 | EUR 47.4 |
Doxorubicin hydrochloride, USP grade |
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GA4969-100 | Glentham Life Sciences | 100 | EUR 150.4 |
Doxorubicin hydrochloride, USP grade |
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GA4969-25 | Glentham Life Sciences | 25 | EUR 67.2 |
Doxorubicin hydrochloride, USP grade |
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GA4969-50 | Glentham Life Sciences | 50 | EUR 95 |
Doxorubicin Hydrochloride (Autophagy inducer) |
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SIH-390-10MG | Stressmarq | 10 mg | EUR 231.6 |
Description: The substance Doxorubicin Hydrochloride is a autophagy inducer. It is synthetically produced and has a purity of >98%. The pure substance is red solid which is soluble in water (50 mM).. |
Doxorubicin Hydrochloride (Autophagy inducer) |
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SIH-390-50MG | Stressmarq | 50 mg | EUR 634.8 |
Description: The substance Doxorubicin Hydrochloride is a autophagy inducer. It is synthetically produced and has a purity of >98%. The pure substance is red solid which is soluble in water (50 mM).. |
Doxorubicin |
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A3966-10 | ApexBio | 10 mg | EUR 129.6 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
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A3966-100 | ApexBio | 100 mg | EUR 282 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
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A3966-25 | ApexBio | 25 mg | EUR 157.2 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
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A3966-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 157.2 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
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A3966-S | ApexBio | Evaluation Sample | EUR 97.2 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
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ADC-P-013 | Creative Biolabs | unit | Ask for price |
Doxorubicin |
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abx188695-1g | Abbexa | 1 g | EUR 560.4 |
Doxorubicin |
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D063-100MG | TOKU-E | 100 mg | EUR 1261.2 |
Doxorubicin |
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D063-25MG | TOKU-E | 25 mg | EUR 386.4 |
Doxorubicin |
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HY-15142A | MedChemExpress | 100mg | EUR 258 |
Doxorubicin HCl |
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20-abx184016 | Abbexa |
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Doxorubicin 10mM |
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TG4120 | TopoGen | 0.25ml | EUR 187.2 |
Doxorubicin HCl, 100mg |
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R2531-100mg | ACTGene | each | EUR 1560 |
Doxorubicin HCl, 10mg |
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R2531-10mg | ACTGene | each | EUR 236.4 |
Adriamycin (Doxorubicin) |
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E1KS1208 | EnoGene | 10mg | EUR 490.8 |
Doxorubicin (Adriamycin) HCl |
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A1832-10 | ApexBio | 10 mg | EUR 150 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin (Adriamycin) HCl |
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A1832-100 | ApexBio | 100 mg | EUR 560.4 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin (Adriamycin) HCl |
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A1832-25 | ApexBio | 25 mg | EUR 226.8 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin (Adriamycin) HCl |
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A1832-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 135.6 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
PEGylated Liposomal Doxorubicin- 2 mg |
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PHPC002DX | ProFoldin | 2 mg | EUR 140.62 |
Description: This product includes 1 ml of liposomal doxorubicin at concentrations of 2 mg/ml doxorubicin and 16 mg/ml of lipids. |
PEGylated Liposomal Doxorubicin- 20 mg |
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PHPC020DX | ProFoldin | 20 mg | EUR 358.62 |
Description: This product includes 10 ml of liposomal doxorubicin at concentrations of 2 mg/ml doxorubicin and 16 mg/ml of lipids. |
Erlotinib, Hydrochloride Salt |
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1588-100 | Biovision | each | EUR 202.8 |
Erlotinib, Hydrochloride Salt |
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1588-1000 | Biovision | each | EUR 477.6 |
Erlotinib, Hydrochloride Salt, >99% |
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BC026-101 | GenDepot | 1g | EUR 327.6 |
Erlotinib, Hydrochloride Salt, >99% |
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BC026-102 | GenDepot | 2g | EUR 465.6 |
Erlotinib, Hydrochloride Salt, >99% |
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BC026-105 | GenDepot | 5g | EUR 684 |
17-DMAG, Hydrochloride Salt, >98% |
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BC024-001 | GenDepot | 1mg | EUR 213.6 |
17-DMAG, Hydrochloride Salt, >98% |
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BC024-005 | GenDepot | 5mg | EUR 343.2 |
17-DMAG, Hydrochloride Salt, >98% |
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BC024-010 | GenDepot | 10mg | EUR 489.6 |
17-DMAG, Hydrochloride Salt, >98% |
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BC024-025 | GenDepot | 25mg | Ask for price |
17-DMAG, Hydrochloride Salt, >99% |
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BC024-100 | GenDepot | 100mg | Ask for price |
17-DMAG, Hydrochloride Salt, >99% |
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BC024-101 | GenDepot | 1g | Ask for price |
17-DMAG, Hydrochloride Salt, >99% |
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BC024-250 | GenDepot | 250mg | Ask for price |
OSU-03012, Hydrochloride Salt, >98% |
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BC061-005 | GenDepot | 5mg | EUR 375.6 |
OSU-03012, Hydrochloride Salt, >98% |
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BC061-025 | GenDepot | 25mg | EUR 634.8 |
Human HeLa (Cervix Adenocarcinoma) Whole Cell Lysate - Doxorubicin Stimulated |
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HCL-2010 | Alpha Diagnostics | 100ug | EUR 255.6 |
Human HeLa (Cervix Adenocarcinoma) Cell Nuclear Extract - Doxorubicin Stimulated |
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HCL-2004 | Alpha Diagnostics | 100ug | EUR 270 |
Doxorubicin.HCl |
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1527-5 | Biovision | each | EUR 183.6 |
L-Leucine 7-amido-4-methylcoumarin hydrochloride salt |
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GC8248-100 | Glentham Life Sciences | 100 | EUR 143.7 |
L-Leucine 7-amido-4-methylcoumarin hydrochloride salt |
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GC8248-25 | Glentham Life Sciences | 25 | EUR 57.8 |
Doxepin (hydrochloride) |
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C4153-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 135.6 |
Description: Doxepin, a tricyclic antidepressant, is a potent histamine H1 antagonist [1]. The histamine receptors belong to a family of G protein?coupled receptors activated by their primary endogenous ligand histamine. |
Doxepin (hydrochloride) |
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C4153-5000 | ApexBio | 5 g | EUR 201.6 |
Description: Doxepin, a tricyclic antidepressant, is a potent histamine H1 antagonist [1]. The histamine receptors belong to a family of G protein?coupled receptors activated by their primary endogenous ligand histamine. |
Doxepin (Hydrochloride) |
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HY-B0725 | MedChemExpress | 500mg | EUR 129.6 |
Doxapram hydrochloride |
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GP6685-100 | Glentham Life Sciences | 100 | EUR 201.9 |
Doxycycline Hydrochloride |
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D065-25MG | TOKU-E | 25mg | EUR 410.4 |
Doxycycline Hydrochloride |
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D065-5MG | TOKU-E | 5mg | EUR 142.8 |
Doxycycline hydrochloride |
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GA4252-1G | Glentham Life Sciences | 1 g | EUR 99.6 |
Doxycycline hydrochloride |
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GA4252-500MG | Glentham Life Sciences | 500 mg | EUR 74.4 |
Doxycycline (hydrochloride) |
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HY-N0565A | MedChemExpress | 1g | EUR 142.8 |
Doxycycline hydrochloride |
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GA4252-1 | Glentham Life Sciences | 1 | EUR 53.1 |
Doxycycline hydrochloride |
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GA4252-500 | Glentham Life Sciences | 500 | EUR 31.7 |
Doxapram (hydrochloride hydrate) |
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HY-B0551A | MedChemExpress | 10mM/1mL | EUR 206.4 |
(±)-Salsolinol (hydrochloride) |
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C4364-500 | ApexBio | 500 mg | EUR 369.6 |
Description: (±)-Salsolinol targets depolarize dopamineric neurons. Dopaminergic neurons produce dopamine, a neurotransmitter with various roles in neurological functions. |
2‐AMINO ACETAMIDE HYDROCHLORIDE (GLYCINAMIDE HYDROCHLORIDE) |
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101003 | Survival Technologies | each | Ask for price |
DOI hydrochloride |
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B5321-10 | ApexBio | 10 mg | EUR 205.2 |
DOI hydrochloride |
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B5321-5 | ApexBio | 5 mg | EUR 141.6 |
DOI hydrochloride |
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B5321-50 | ApexBio | 50 mg | EUR 714 |
DOB hydrochloride |
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B5344-1 | ApexBio | 1 mg | EUR 141.6 |
Q94 hydrochloride |
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B5705-10 | ApexBio | 10 mg | EUR 350.4 |
Q94 hydrochloride |
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B5705-50 | ApexBio | 50 mg | EUR 1264.8 |
GMQ hydrochloride |
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B5793-10 | ApexBio | 10 mg | EUR 212.4 |
GMQ hydrochloride |
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B5793-50 | ApexBio | 50 mg | EUR 711.6 |
AMT hydrochloride |
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B6480-10 | ApexBio | 10 mg | EUR 205.2 |
AMT hydrochloride |
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B6480-100 | ApexBio | 100 mg | EUR 1036.8 |
AMT hydrochloride |
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B6480-5 | ApexBio | 5 mg | EUR 141.6 |
AMT hydrochloride |
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B6480-50 | ApexBio | 50 mg | EUR 673.2 |
EDC hydrochloride |
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GP0849-100G | Glentham Life Sciences | 100 g | EUR 141.6 |
EDC hydrochloride |
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GP0849-250G | Glentham Life Sciences | 250 g | EUR 237.6 |
EDC hydrochloride |
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GP0849-25G | Glentham Life Sciences | 25 g | EUR 84 |
EDC hydrochloride |
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GP0849-5G | Glentham Life Sciences | 5 g | EUR 55.2 |
SAG (hydrochloride) |
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HY-12848B | MedChemExpress | 10mg | EUR 321.6 |
BEC (hydrochloride) |
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HY-19548A | MedChemExpress | 25mg | EUR 570 |
EDC hydrochloride |
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GP0849-100 | Glentham Life Sciences | 100 | EUR 87.1 |
EDC hydrochloride |
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GP0849-25 | Glentham Life Sciences | 25 | EUR 39.4 |
EDC hydrochloride |
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GP0849-250 | Glentham Life Sciences | 250 | EUR 166 |
EDC hydrochloride |
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GP0849-5 | Glentham Life Sciences | 5 | EUR 15.9 |
EHNA hydrochloride |
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2265-25 | Biovision | each | EUR 339.6 |
EHNA hydrochloride |
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2265-5 | Biovision | each | EUR 138 |
MPEP Hydrochloride |
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A3633-10 | ApexBio | 10 mg | EUR 142.8 |
Description: IC50: 36 nMMPEP is a potent, selective and systemically active mGlu5 receptor antagonist. Metabotropic glutamate (mGlu) receptors are a of G-protein-coupled receptor family linked to multiple second messengers and modulation of ion channel functions in the nervous system. |
MPEP Hydrochloride |
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A3633-50 | ApexBio | 50 mg | EUR 379.2 |
Description: IC50: 36 nMMPEP is a potent, selective and systemically active mGlu5 receptor antagonist. Metabotropic glutamate (mGlu) receptors are a of G-protein-coupled receptor family linked to multiple second messengers and modulation of ion channel functions in the nervous system. |
MPTP hydrochloride |
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A3634-10 | ApexBio | 10 mg | EUR 162 |
Description: IC50 Value: 53uM?inhibited the nerve-evoked twitches of phrenic nerve-hemidiaphragm preparations from ICR mice? . MPTP HCl (Sigma-Chem.) induced reduction in the DOPAC HVA/dopamine (DA) ratio and increase in striatal ascorbate (AS) oxidation in rats [1]. |
MPTP hydrochloride |
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A3634-50 | ApexBio | 50 mg | EUR 344.4 |
Description: IC50 Value: 53uM?inhibited the nerve-evoked twitches of phrenic nerve-hemidiaphragm preparations from ICR mice? . MPTP HCl (Sigma-Chem.) induced reduction in the DOPAC HVA/dopamine (DA) ratio and increase in striatal ascorbate (AS) oxidation in rats [1]. |
MTEP hydrochloride |
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A3636-10 | ApexBio | 10 mg | EUR 205.2 |
Description: IC50: 5 nMMTEP is a selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonist.The mGluRs are classified into three groups: group I (mGluR1 and 5), group II (mGluR2 and 3) and group III (mGluR4, 6, 7 and 8). |
MTEP hydrochloride |
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A3636-5 | ApexBio | 5 mg | EUR 153.6 |
Description: IC50: 5 nMMTEP is a selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonist.The mGluRs are classified into three groups: group I (mGluR1 and 5), group II (mGluR2 and 3) and group III (mGluR4, 6, 7 and 8). |
MTEP hydrochloride |
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A3636-50 | ApexBio | 50 mg | EUR 686.4 |
Description: IC50: 5 nMMTEP is a selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonist.The mGluRs are classified into three groups: group I (mGluR1 and 5), group II (mGluR2 and 3) and group III (mGluR4, 6, 7 and 8). |
PJ34 hydrochloride |
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A4159-10 | ApexBio | 10 mg | EUR 142.8 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
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A4159-5 | ApexBio | 5 mg | EUR 129.6 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
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A4159-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 150 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
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A4159-50 | ApexBio | 50 mg | EUR 296.4 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
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A4159-S | ApexBio | Evaluation Sample | EUR 97.2 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
THZ1 hydrochloride |
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9544-25 | Biovision | each | EUR 1227.6 |
THZ1 hydrochloride |
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9544-5 | Biovision | each | EUR 366 |
MPEP hydrochloride |
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B1151-10 | Biovision | each | EUR 222 |
MPEP hydrochloride |
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B1151-50 | Biovision | each | EUR 705.6 |
S1RA hydrochloride |
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B1180-10 | ApexBio | 10 mg | EUR 1144.8 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
S1RA hydrochloride |
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B1180-100 | ApexBio | 100 mg | EUR 4620 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
S1RA hydrochloride |
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B1180-5 | ApexBio | 5 mg | EUR 819.6 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
S1RA hydrochloride |
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B1180-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 895.2 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
S1RA hydrochloride |
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B1180-50 | ApexBio | 50 mg | EUR 3316.8 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
MMAD hydrochloride |
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ADC-P-019 | Creative Biolabs | unit | Ask for price |
MMAF Hydrochloride |
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ADC-P-021 | Creative Biolabs | unit | Ask for price |
TAME Hydrochloride |
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2050-100 | Biovision | each | EUR 151.2 |
TAME Hydrochloride |
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2050-1000 | Biovision | each | EUR 574.8 |
TAME Hydrochloride |
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2050-500 | Biovision | each | EUR 405.6 |
THZ1 Hydrochloride |
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B4736-10 | ApexBio | 10 mg | EUR 268.8 |
Description: THZ1 is a covalent inhibitor of CDK7 with IC50 value of 3.2nM [1].THZ1 covalently modifies CDK7 by targeting C312 residue outside of the kinase domain, providing an unanticipated means of achieving covalent selectivity. |
THZ1 Hydrochloride |
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B4736-25 | ApexBio | 25 mg | EUR 477.6 |
Description: THZ1 is a covalent inhibitor of CDK7 with IC50 value of 3.2nM [1].THZ1 covalently modifies CDK7 by targeting C312 residue outside of the kinase domain, providing an unanticipated means of achieving covalent selectivity. |
THZ1 Hydrochloride |
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B4736-5 | ApexBio | 5 mg | EUR 170.4 |
Description: THZ1 is a covalent inhibitor of CDK7 with IC50 value of 3.2nM [1].THZ1 covalently modifies CDK7 by targeting C312 residue outside of the kinase domain, providing an unanticipated means of achieving covalent selectivity. |
THZ1 Hydrochloride |
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B4736-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 205.2 |
Description: THZ1 is a covalent inhibitor of CDK7 with IC50 value of 3.2nM [1].THZ1 covalently modifies CDK7 by targeting C312 residue outside of the kinase domain, providing an unanticipated means of achieving covalent selectivity. |
TCEP hydrochloride |
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B6055-10000 | ApexBio | 10 g | EUR 338.4 |
Description: Tris(2-carboxyethyl)phosphine hydrochloride (TCEP HCL) is a water soluble strong reducing agent that cleave disulfide bonds. It is a non-thiol and non-volatile solid. |
TCEP hydrochloride |
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B6055-2000 | ApexBio | 2 g | EUR 150 |
Description: Tris(2-carboxyethyl)phosphine hydrochloride (TCEP HCL) is a water soluble strong reducing agent that cleave disulfide bonds. It is a non-thiol and non-volatile solid. |
TCEP hydrochloride |
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B6055-50000 | ApexBio | 50 g | EUR 1243.2 |
Description: Tris(2-carboxyethyl)phosphine hydrochloride (TCEP HCL) is a water soluble strong reducing agent that cleave disulfide bonds. It is a non-thiol and non-volatile solid. |
HEAT hydrochloride |
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B6339-10 | ApexBio | 10 mg | EUR 321.6 |
HEAT hydrochloride |
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B6339-50 | ApexBio | 50 mg | EUR 1167.6 |
THIP hydrochloride |
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B6460-100 | ApexBio | 100 mg | EUR 358.8 |
THIP hydrochloride |
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B6460-25 | ApexBio | 25 mg | EUR 174 |
THIP hydrochloride |
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B6460-50 | ApexBio | 50 mg | EUR 243.6 |
AMTB hydrochloride |
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B2978-25 | Biovision | 25 mg | EUR 812.4 |
AMTB hydrochloride |
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B2978-5 | Biovision | 5 mg | EUR 247.2 |
DMCM hydrochloride |
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B7268-10 | ApexBio | 10 mg | EUR 385.2 |
DMCM hydrochloride |
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B7268-100 | ApexBio | 100 mg | EUR 2210.4 |
DMCM hydrochloride |
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B7268-25 | ApexBio | 25 mg | EUR 776.4 |
DMCM hydrochloride |
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B7268-5 | ApexBio | 5 mg | EUR 277.2 |
DMCM hydrochloride |
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B7268-5.1 | ApexBio | 10 mM (in 1mL H2O) | EUR 297.6 |
DMCM hydrochloride |
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B7268-50 | ApexBio | 50 mg | EUR 1363.2 |
TRIS hydrochloride |
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B7299-500000 | ApexBio | 500 g | EUR 309.6 |
AMTB hydrochloride |
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B7559-10 | ApexBio | 10 mg | EUR 459.6 |
AMTB hydrochloride |
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B7559-50 | ApexBio | 50 mg | EUR 1746 |
EHNA hydrochloride |
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B6662-10 | ApexBio | 10 mg | EUR 145.2 |
EHNA hydrochloride |
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B6662-25 | ApexBio | 25 mg | EUR 262.8 |
N20C hydrochloride |
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B6980-10 | ApexBio | 10 mg | EUR 340.8 |
N20C hydrochloride |
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B6980-50 | ApexBio | 50 mg | EUR 1245.6 |
TMPH hydrochloride |
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B7053-10 | ApexBio | 10 mg | EUR 321.6 |
TMPH hydrochloride |
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B7053-50 | ApexBio | 50 mg | EUR 1167.6 |
DAPI (hydrochloride) |
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C3362-10 | ApexBio | 10 mg | EUR 146.4 |
DAPI (hydrochloride) |
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C3362-25 | ApexBio | 25 mg | EUR 240 |
DAPI (hydrochloride) |
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C3362-5 | ApexBio | 5 mg | EUR 111.6 |
AD57 (hydrochloride) |
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C3080-1 | ApexBio | 1 mg | EUR 141.6 |
Description: IC50: 2 nM: blocks the receptor tyrosine kinase RET in Drosophila.AD57, as a polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer. |
AD57 (hydrochloride) |
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C3080-10 | ApexBio | 10 mg | EUR 714 |
Description: IC50: 2 nM: blocks the receptor tyrosine kinase RET in Drosophila.AD57, as a polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer. |
AD57 (hydrochloride) |
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C3080-5 | ApexBio | 5 mg | EUR 428.4 |
Description: IC50: 2 nM: blocks the receptor tyrosine kinase RET in Drosophila.AD57, as a polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer. |
EDAC, hydrochloride |
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EB0433 | Bio Basic | 25g | EUR 123.68 |
TAME Hydrochloride |
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GM4942-5G | Glentham Life Sciences | 5 g | EUR 90 |
TRIS hydrochloride |
|||
GB4431-100G | Glentham Life Sciences | 100 g | EUR 64.8 |
TRIS hydrochloride |
|||
GB4431-1KG | Glentham Life Sciences | 1 kg | EUR 160.8 |
TRIS hydrochloride |
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GB4431-250G | Glentham Life Sciences | 250 g | EUR 76.8 |
TRIS hydrochloride |
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GB4431-500G | Glentham Life Sciences | 500 g | EUR 103.2 |
TRIS hydrochloride |
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GB4431-5KG | Glentham Life Sciences | 5 kg | EUR 486 |
ACHP (Hydrochloride) |
|||
HY-13060 | MedChemExpress | 100mg | EUR 1861.2 |
MTEP (hydrochloride) |
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HY-13206 | MedChemExpress | 10mg | EUR 200.4 |
TAME hydrochloride |
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HY-13255A | MedChemExpress | 100mg | EUR 192 |
TCEP (hydrochloride) |
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HY-W011500 | MedChemExpress | 10mM/1mL | EUR 135.6 |
MCLA hydrochloride |
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HY-W013275 | MedChemExpress | 5mg | EUR 381.6 |
DMCM (hydrochloride) |
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HY-100369A | MedChemExpress | 100mg | EUR 1695.6 |
OABK (hydrochloride) |
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HY-100825 | MedChemExpress | 100mg | EUR 3531.6 |
EIPA (hydrochloride) |
|||
HY-101840A | MedChemExpress | 10mM/1mL | EUR 151.2 |
(±)-ANAP hydrochloride |
|||
HY-101937C | MedChemExpress | 5mg | EUR 817.2 |
EHNA (hydrochloride) |
|||
HY-103160A | MedChemExpress | 5mg | EUR 170.4 |
PJ34 (hydrochloride) |
|||
HY-13688 | MedChemExpress | 10mg | EUR 159.6 |
MPEP (Hydrochloride) |
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HY-14609 | MedChemExpress | 50mg | EUR 439.2 |
S107 hydrochloride |
|||
HY-15292A | MedChemExpress | 50mg | EUR 804 |
Inhibitory Potential of Polyclonal Camel Antibodies towards New Delhi Metallo-β-lactamase-1 (NDM-1)
New Delhi Metallo-β-lactamase-1 (NDM-1) is probably the most prevalent kind of metallo-β-lactamase, in a position to hydrolyze virtually all antibiotics of the β-lactam group, resulting in multidrug-resistant micro organism. Up to now, there aren’t any clinically related inhibitors to combat NDM-1. Using dromedary polyclonal antibody inhibitors towards NDM-1 represents a promising new class of molecules with inhibitory exercise.
Within the present research, immunoreactivities of dromedary Immunoglobulin G (IgG) isotypes containing heavy-chain and standard antibodies had been examined after profitable immunization of dromedary utilizing growing quantities of the recombinant NDM-1 enzyme. Inhibition kinetic assays, carried out utilizing a spectrophotometric methodology with nitrocefin as a reporter substrate, demonstrated that IgG1, IgG2, and IgG3 had been in a position to inhibit not solely the hydrolytic exercise of NDM-1 but in addition Verona integron-encoded metallo-β-lactamase (VIM-1) (subclass B1) and L1 metallo-β-lactamase (L1) (subclass B3) with inhibitory focus (IC50) values starting from 100 to 0.04 μM.
Investigations on the flexibility of IgG subclasses to cut back the expansion of recombinant Escherichia coli BL21(DE3)/codon plus cells containing the recombinant plasmid expressing NDM-1, L1, or VIM-1 confirmed that the addition of IgGs (four and eight mg/L) to the cell tradition was unable to revive the susceptibility of carbapenems.
Apparently, IgGs had been in a position to work together with NDM-1, L1, and VIM-1 when examined on the periplasm extract of every cultured pressure. The inhibitory focus was within the micromolar vary for all β-lactams examined. A visualization of the 3D structural foundation utilizing the three enzyme Protein Knowledge Financial institution (PDB) recordsdata helps preliminarily the recorded inhibition of the three MBLs.
A Easy and Environment friendly Genetic Immunization Protocol for the Manufacturing of Extremely Particular Polyclonal and Monoclonal Antibodies towards the Native Type of Mammalian Proteins
We’ve got generated polyclonal and monoclonal antibodies by genetic immunization over the past twenty years. On this paper, we current our most profitable methodology acquired over these years and current the animals by which we obtained the very best charges of success. The method introduced is handy, simple, inexpensive, and generates antibodies towards mammalian proteins of their native type.
This protocol requires neither costly gear, resembling a gene gun, nor subtle methods such because the conjugation of gold microspheres, electroporation, or surgical procedure to inject in lymph nodes. The protocol introduced makes use of merely the purified plasmid expressing the protein of curiosity below a powerful promoter, which is injected at intramuscular and intradermal websites.
This method was examined in 5 species. Guinea pigs had been the animals of alternative for the manufacturing of polyclonal antibodies. Monoclonal antibodies could possibly be generated in mice by giving, as a final injection, a suspension of transfected cells. The antibodies detected their antigens of their native kinds. They had been extremely particular with very low non-specific background ranges, as assessed by immune-blots, immunocytochemistry, immunohistochemistry and circulation cytometry. We current herein an in depth and easy process to efficiently elevate particular antibodies towards native proteins.
Manufacturing of a polyclonal antibody towards inosine-uridine preferring nucleoside hydrolase of Acanthamoeba castellanii and its entry to prognosis of Acanthamoeba keratitis
Acanthamoeba keratitis (AK) is a uncommon illness however its prevalence all through the globe continues to develop, primarily as a result of elevated contact lens utilization. Since early-stage signs related to AK carefully resemble these from different corneal infections, correct prognosis is tough and this typically leads to delayed therapy and exacerbation of the illness, which might result in everlasting visible impairment. Accordingly, creating a speedy Acanthamoeba-specific diagnostic methodology is very desired.
Within the current research, a speedy and . Among the many huge portions of proteins secreted by the pathogenic Acanthamoeba, an open studying body of the inosine-uridine preferring nucleoside hyddifferential methodology for AK prognosis was developed utilizing the secretory proteins derived from the pathogenic Acanthamoebarolase (IPNH) gene was obtained. After expressing and purifying the IPNH protein utilizing the pGEX 4T-Three vector system, mice had been immunized with the purified proteins for polyclonal antibody technology.
Western blot was carried out utilizing protein lysates of the human corneal cell, non-pathogenic amoeba, pathogenic amoeba, and scientific amoeba isolate together with lysates from different causes of keratitis resembling Staphylococcus aureus, Pseudomonas aeruginosa, and Fusarium solani to verify Acanthamoeba-specificity.
Western blot utilizing the polyclonal IPNH antibody revealed that IPNH was Acanthamoeba-specific since these proteins had been solely noticed in lysates of Acanthamoeba origin or its tradition media. Our findings point out that the IPNH antibody of Acanthamoeba might function a possible agent for speedy and differential AK prognosis.
RIPA Lysis Buffer (Strong) |
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HY-K1001 | MedChemExpress | 100 mL | EUR 176.4 |
Pierce Seal Strong Sheets |
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PCR0632 | Scientific Laboratory Supplies | PK100 | EUR 124.8 |
Pierce Seal Strong Roll610mX78mm |
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PCR0628 | Scientific Laboratory Supplies | 1ROLL | EUR 981.6 |
PCR Foil Seal Strong Sheets |
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PCR0528 | Scientific Laboratory Supplies | PK100 | EUR 188.4 |
Tweezers Fine Strong CF Tips |
|||
INS5058 | Scientific Laboratory Supplies | EACH | EUR 33.42 |
Tweezers Flat Strong CF Tips |
|||
INS5100 | Scientific Laboratory Supplies | EACH | EUR 39.04 |
Pierce Seal Strong Sample Roll |
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PCR0630 | Scientific Laboratory Supplies | 1ROLL | EUR 53.01 |
replacement tip Kit strong thick |
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INS2090 | Scientific Laboratory Supplies | EACH | EUR 10.35 |
replacement tip Kit strong point |
|||
INS2094 | Scientific Laboratory Supplies | EACH | EUR 10.35 |
replacement tip Kit strong thick |
|||
INS2058 | Scientific Laboratory Supplies | EACH | EUR 10.35 |
EP Reagent Sodium Hydroxide Sol. Strong |
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1081404 | Scientific Laboratory Supplies | 1L | EUR 170.4 |
EP Reagent Sodium Hypochlorite Sol. Strong |
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10816005 | Scientific Laboratory Supplies | 500ML | EUR 121.2 |
Magnetic Base Support Z w/ Strong Magnet - 34.5mm |
|||
M-R-1013161 | MiTeGen | 1 UNIT | EUR 46 |
Description: Magnetic Base Support Z w/ Strong Magnet - 34.5mm |
Magnetic Base Support Z w/ Strong Magnet - 27.5mm |
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M-R-1015229 | MiTeGen | 1 UNIT | EUR 46 |
Description: Magnetic Base Support Z w/ Strong Magnet - 27.5mm |
Genistin |
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1535-10 | Biovision | each | EUR 196.8 |
Genistin |
|||
N1860-20 | ApexBio | 20 mg | EUR 268.8 |
Description: Actions Inactive analog of genistein; useful as a negative control for genistein and other tyrosine kinase inhibitors. Selective inhibitor of mammalian terminal deoxynucleotidyl transferase (TdT),with no measurable effect on mammalian or microbial DNA p |
Genistin |
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HY-N0595 | MedChemExpress | 50mg | EUR 170.4 |
Genistin |
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TB0370-1000 | ChemNorm | 4X20mg | EUR 321.6 |
Genistin |
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GC2802-10 | Glentham Life Sciences | 10 | EUR 242.4 |
Genistin |
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GC2802-100 | Glentham Life Sciences | 100 | EUR 960.1 |
Genistin |
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GC2802-25 | Glentham Life Sciences | 25 | EUR 382.3 |
Genistin |
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GC2802-250 | Glentham Life Sciences | 250 | EUR 1845.7 |
Genistin |
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GC2802-50 | Glentham Life Sciences | 50 | EUR 577.8 |
Genistin, >99% |
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BC034-025 | GenDepot | 25mg | EUR 278.4 |
Genistin, >99% |
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BC034-050 | GenDepot | 50mg | EUR 327.6 |
Genistin, >99% |
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BC034-100 | GenDepot | 100mg | EUR 537.6 |
Genistin(Genistoside) |
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E1KS2301 | EnoGene | 25mg | EUR 390 |
Genistin malonate |
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TB0588-0005 | ChemNorm | 10mg | EUR 886.8 |
Optically clear sealing film for qPCR, Strong Bond, for PP plates, 100/pk |
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MS1000-PCR2 | Benchmark Scientific | 1 each | EUR 145 |
Foil seals, strong bonding for cold storage (-200 to 110°C) and DMSO, for PP plates, 100/pk |
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MS1000-F2 | Benchmark Scientific | 1 each | EUR 145 |
Strongzyme Goat anti Mouse IgG (H+L) (HRP) |
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43R-1653 | Fitzgerald | 1 ml | EUR 763.2 |
Description: Strongzyme Goat anti-Mouse IgG (H+L) secondary antibody (HRP) |
Strongzyme Rabbit anti Goat IgG (H+L) (HRP) |
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43R-1650 | Fitzgerald | 1 ml | EUR 940.8 |
Description: Strongzyme Rabbit anti Goat IgG (H + L) (HRP) secondary antibody |
Strongzyme Goat anti Rabbit IgG (H + L) (HRP) |
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43R-1652 | Fitzgerald | 1 ml | EUR 763.2 |
Description: Strongzyme Goat anti Rabbit IgG (H + L) secondary antibody (HRP) |
QPCR Kit DNA Strongylus vulgaris |
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MOL8940 | Scientific Laboratory Supplies | EACH | EUR 1004.01 |
QPCR Kit DNA Strongylus vulgaris |
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MOL8942 | Scientific Laboratory Supplies | EACH | EUR 1274.27 |
Strongyloides (IgG/IgM) ELISA Kit (Human) (OKNA00174) |
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OKNA00174 | Aviva Systems Biology | 96 Wells | EUR 505.2 |
Description: Description of target: Strongyloides is a genus containing some 50 species of obligate gastrointestinal parasites of vertebrates. Strongyloides stercoralis is the scientific name of a human parasitic roundworm causing the disease of strongyloidiasis. Its common name is pinworm in the UK and threadworm in the US. The Strongyloides stercoralis nematode can parasitize humans. The adult parasitic stage lives in tunnels in the mucosa of the small intestine.S. stercoralis can be found in areas with tropical and subtropical climates but cases also occur in temperate area, more frequently in rural areas. S. stercoralis has a very low prevalence in societies where fecal contamination of soil or water is rare. Many people infected are usually asymptomatic at first. Symptoms include dermatitis: swelling, itching, larva currens, and mild hemorrhage at the site where the skin has been penetrated. If the parasite reaches the lungs, the chest may feel as if it is burning, and wheezing and coughing may result, along with pneumonia-like symptoms (Löffler's syndrome). The intestines could eventually be invaded, leading to burning pain, tissue damage, sepsis, and ulcers. In severe cases, edema may result in obstruction of the intestinal tract, as well as loss of peristaltic contractions. Strongyloides infection in immunocompromised individuals (particularly following the administration of steroids, for example following transplant surgery) can result in disseminated strongyloidiasis, in which worms move beyond the confines of the gut into other organs. This is fatal unless antiStrongyloides therapy is given.Locating juvenile larvae, either rhabditiform or filariform, in recent stool samples will confirm the presence of this parasite. Other techniques used include direct fecal smears, culturing fecal samples on agar plates, serodiagnosis through ELISA, and duodenal fumigation.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Reverse Capture Sandwich ELISA ;Sensitivity: Sensitivity is determined as the probability of the assay indicating a positive score in samples with the specific analyte present: 87.9% |
StrongZyme Streptavidin-PolyHRP (High Load) |
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43R-1645 | Fitzgerald | 1 mg | EUR 369.6 |
Description: StrongZyme Streptavidin-PolyHRP conjugate (High Load) |
Strontium Oxide |
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abx186564-500g | Abbexa | 500 g | EUR 309.6 |
Strontium oxide, 99.5% |
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GX8751-50 | Glentham Life Sciences | 50 | EUR 585.6 |
ICP Std Strontium 1000ug/mL in 2-5% HCl |
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PSR2A3 | Scientific Laboratory Supplies | 100ML | EUR 120.12 |
ICP Std Strontium 1000ug/mL in 2-5% HCl |
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PSR2B3 | Scientific Laboratory Supplies | 250ML | EUR 214.12 |
ICP Std Strontium 1000ug/mL in 2-5% HCl |
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PSR2C3 | Scientific Laboratory Supplies | 500ML | EUR 265.04 |
ICP Std Strontium 10000ug/mL in 2-5% HCl |
|||
PSR4A3 | Scientific Laboratory Supplies | 100ML | EUR 208.9 |
ICP Std Strontium 10000ug/mL in 2-5% HCl |
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PSR4B3 | Scientific Laboratory Supplies | 250ML | EUR 352.51 |
Strontium bromide, 99.99% |
|||
GX4255-10 | Glentham Life Sciences | 10 | EUR 325.9 |
Strontium nitrate, 99.999% |
|||
GX6363-50 | Glentham Life Sciences | 50 | EUR 391 |
Strontium nitrate, 99.99% |
|||
GX1574-50 | Glentham Life Sciences | 50 | EUR 280.7 |
Strontium Ranelate |
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A8526-10 | ApexBio | 10 mg | EUR 397.2 |
Description: Strontium Ranelate is a bone metabolism modulator that inhibits bone resorption while maintaining bone formation. Commonly used as an antiosteoporotic. |
Strontium chloride |
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B7708-50 | ApexBio | 50 mg | EUR 154.8 |
Strontium Ranelate |
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HY-17397 | MedChemExpress | 500mg | EUR 820.8 |
ICP Std Strontium 100ug/mL in 2-5% HNO3 |
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PSR1A2 | Scientific Laboratory Supplies | 100ML | EUR 117.5 |
ICP Std Strontium 1000ug/mL in 2-5% HNO3 |
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PSR2B2 | Scientific Laboratory Supplies | 250ML | EUR 214.12 |
ICP Std Strontium 1000ug/mL in 2-5% HNO3 |
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PSR2C2 | Scientific Laboratory Supplies | 500ML | EUR 261.6 |
ICP Std Strontium 10000ug/mL in 2-5% HNO3 |
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PSR4A2 | Scientific Laboratory Supplies | 100ML | EUR 208.9 |
ICP Std Strontium 10000ug/mL in 2-5% HNO3 |
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PSR4B2 | Scientific Laboratory Supplies | 250ML | EUR 355.12 |
ICP Std Strontium 10000ug/mL in 3.5% HNO3 |
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PSR4B4-500ML | Scientific Laboratory Supplies | 500ML | EUR 671.08 |
Strontium fluoride, 99% |
|||
GX3818-250 | Glentham Life Sciences | 250 | EUR 137.2 |
Strontium titanate, 99.9% |
|||
GX4862-100 | Glentham Life Sciences | 100 | EUR 340.5 |
Strontium titanate, 99.9% |
|||
GX4862-25 | Glentham Life Sciences | 25 | EUR 164.5 |
Strontium fluoride, 99.99% |
|||
GX7221-10 | Glentham Life Sciences | 10 | EUR 134.1 |
Strontium fluoride, 99.99% |
|||
GX7221-25 | Glentham Life Sciences | 25 | EUR 286.8 |
Strontium fluoride, 99.99% |
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GX7221-50 | Glentham Life Sciences | 50 | EUR 562.1 |
Strontium fluoride, 99.9% |
|||
GX8262-10 | Glentham Life Sciences | 10 | EUR 116.1 |
Strontium fluoride, 99.9% |
|||
GX8262-50 | Glentham Life Sciences | 50 | EUR 280.2 |
Strontium titanate, 99+% |
|||
GX1727-250 | Glentham Life Sciences | 250 | EUR 108.5 |
AAS Strontium Std 1000ppm in 0.5M HNO3 |
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AASRH | Scientific Laboratory Supplies | 500ML | EUR 246 |
AAS Strontium Std 10000ppm in 1M HNO3 |
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AASRM | Scientific Laboratory Supplies | 500ML | EUR 356.4 |
Flame Std Strontium 1000ppm |
|||
FISR1 | Scientific Laboratory Supplies | 500ML | EUR 190.8 |
Strontium aluminate, 99+% |
|||
GX5543-10 | Glentham Life Sciences | 10 | EUR 113.1 |
Strontium aluminate, 99+% |
|||
GX5543-50 | Glentham Life Sciences | 50 | EUR 262.3 |
Strontium carbonate, 99.999% |
|||
GX5614-25 | Glentham Life Sciences | 25 | EUR 258.5 |
Strontium zirconate, 99+% |
|||
GX8495-250 | Glentham Life Sciences | 250 | EUR 120.5 |
Strontium molybdate, 99.9% |
|||
GX0022-50 | Glentham Life Sciences | 50 | EUR 189 |
Strontium tungstate, 99.9% |
|||
GX0472-10 | Glentham Life Sciences | 10 | EUR 101 |
Strontium tungstate, 99.9% |
|||
GX0472-50 | Glentham Life Sciences | 50 | EUR 233 |
Strontium carbonate |
|||
GK8492-1 | Glentham Life Sciences | 1 | EUR 50.3 |
Strontium carbonate |
|||
GK8492-250 | Glentham Life Sciences | 250 | EUR 25.5 |
Strontium carbonate |
|||
GK8492-5 | Glentham Life Sciences | 5 | EUR 176.1 |
Strontium carbonate, 99+% |
|||
GX9308-100 | Glentham Life Sciences | 100 | EUR 129.6 |
Strontium carbonate, 99+% |
|||
GX9308-250 | Glentham Life Sciences | 250 | EUR 229.6 |
IC Cation Std Strontium 200ppm in H2O |
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ICCT43 | Scientific Laboratory Supplies | 100ML | EUR 135.6 |
ICP Standard Strontium 2-5pc |
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PSR2A2 | Scientific Laboratory Supplies | 100ML | EUR 221.95 |
Strontium Pieces max. 8 mm, under oil, 99.2+% |
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GX0495-25 | Glentham Life Sciences | 25 | EUR 1023.2 |
IC Cation Std Strontium 1000ppm in 0.005% HNO3 |
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ICCB43 | Scientific Laboratory Supplies | 500ML | EUR 406.8 |
IC Cation Std Strontium 1000ppm in 0.005% HNO3 |
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ICCS43 | Scientific Laboratory Supplies | 100ML | EUR 157.98 |
IC Cation Std Strontium 100ppm in 0.005% HNO3 |
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ICCU43 | Scientific Laboratory Supplies | 100ML | EUR 137.09 |
Strontium acetate hydrate, 99+% |
|||
GX5175-100 | Glentham Life Sciences | 100 | EUR 126.5 |
Strontium chloride hydrate, 99.99+% |
|||
GX6973-10 | Glentham Life Sciences | 10 | EUR 172.7 |
Strontium nitrate, anhydrous, 98% |
|||
GK5693-1KG | Glentham Life Sciences | 1 kg | EUR 98.4 |
Strontium nitrate, anhydrous, 98% |
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GK5693-250G | Glentham Life Sciences | 250 g | EUR 60 |
Strontium nitrate, anhydrous, 98% |
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GK5693-5KG | Glentham Life Sciences | 5 kg | EUR 255.6 |
Strontium nitrate, anhydrous, 98% |
|||
GK5693-1 | Glentham Life Sciences | 1 | EUR 51.4 |
Strontium nitrate, anhydrous, 98% |
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GK5693-250 | Glentham Life Sciences | 250 | EUR 19.8 |
Strontium nitrate, anhydrous, 98% |
|||
GK5693-5 | Glentham Life Sciences | 5 | EUR 182 |
Strontium titanate Nanopowder, 99.9% |
|||
GX7135-1 | Glentham Life Sciences | 1 | EUR 633.8 |
Strontium titanate Nanopowder, 99.9% |
|||
GX7135-100 | Glentham Life Sciences | 100 | EUR 192.2 |
Strontium titanate Nanopowder, 99.9% |
|||
GX7135-250 | Glentham Life Sciences | 250 | EUR 281.9 |
Strontium titanate Nanopowder, 99.9% |
|||
GX7135-50 | Glentham Life Sciences | 50 | EUR 116.1 |
Strontium titanate-Nano Powder, 99.8% |
|||
GX8434-100 | Glentham Life Sciences | 100 | EUR 192.2 |
Strontium titanate-Nano Powder, 99.8% |
|||
GX8434-250 | Glentham Life Sciences | 250 | EUR 373 |
Strontium titanate-Nano Powder, 99.8% |
|||
GX8434-50 | Glentham Life Sciences | 50 | EUR 116.1 |
Strontium chloride hexahydrate |
|||
GK3876-1KG | Glentham Life Sciences | 1 kg | EUR 132 |
Strontium chloride hexahydrate |
|||
GK3876-500G | Glentham Life Sciences | 500 g | EUR 91.2 |
Strontium chloride hexahydrate |
|||
GK3876-5KG | Glentham Life Sciences | 5 kg | EUR 370.8 |
Strontium chloride hexahydrate |
|||
GK3876-1 | Glentham Life Sciences | 1 | EUR 79.1 |
Strontium chloride hexahydrate |
|||
GK3876-5 | Glentham Life Sciences | 5 | EUR 276.9 |
Strontium chloride hexahydrate |
|||
GK3876-500 | Glentham Life Sciences | 500 | EUR 45.9 |
Genistein |
|||
1533-10 | Biovision | each | EUR 164.4 |
Genistein |
|||
1533-100 | Biovision | each | EUR 326.4 |
Genistein |
|||
A2198-100 | ApexBio | 100 mg | EUR 129.6 |
Description: Phytoestrogen with a wide range of biological actions. Inhibits protein tyrosine kinases including epidermal growth factor receptor kinase. Also binds to PPAR? and estrogen receptors and acts as an agonist at GPR30. Also available as part of the MAP |
Genistein |
|||
A2198-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 135.6 |
Description: Phytoestrogen with a wide range of biological actions. Inhibits protein tyrosine kinases including epidermal growth factor receptor kinase. Also binds to PPAR? and estrogen receptors and acts as an agonist at GPR30. Also available as part of the MAP |
Genistein |
|||
20-abx076504 | Abbexa |
|
|
Genistein, >99% |
|||
BC033-101 | GenDepot | 1g | EUR 278.4 |
Genistein, >99% |
|||
BC033-105 | GenDepot | 5g | EUR 457.2 |
Genistein, >99% |
|||
BC033-110 | GenDepot | 10g | EUR 813.6 |
Genistein |
|||
20-abx184098 | Abbexa |
|
|
Genistein |
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GP7710-100MG | Glentham Life Sciences | 100 mg | EUR 180 |
Genistein |
|||
GP7710-10MG | Glentham Life Sciences | 10 mg | EUR 92.4 |
Genistein |
|||
GP7710-250MG | Glentham Life Sciences | 250 mg | EUR 237.6 |
Genistein |
|||
GP7710-50MG | Glentham Life Sciences | 50 mg | EUR 154.8 |
Genistein |
|||
GP7710-5MG | Glentham Life Sciences | 5 mg | EUR 74.4 |
Genistein |
|||
HY-14596 | MedChemExpress | 100mg | EUR 142.8 |
Genistein |
|||
TB0320-0500 | ChemNorm | 8XX25mg | EUR 328.8 |
Genistein |
|||
GP7710-10 | Glentham Life Sciences | 10 | EUR 74.7 |
Genistein |
|||
GP7710-100 | Glentham Life Sciences | 100 | EUR 118.7 |
Genistein |
|||
GP7710-250 | Glentham Life Sciences | 250 | EUR 180.9 |
Genistein |
|||
GP7710-5 | Glentham Life Sciences | 5 | EUR 31.7 |
Genistein |
|||
GP7710-50 | Glentham Life Sciences | 50 | EUR 116.1 |
Strontium ranelate heptahydrate |
|||
20-abx184380 | Abbexa |
|
|
Strontium hydroxide, octahydrate, 99+% |
|||
GX1288-1 | Glentham Life Sciences | 1 | EUR 101 |
Strontium hydroxide, octahydrate, 99+% |
|||
GX1288-500 | Glentham Life Sciences | 500 | EUR 84.4 |
Assurance Grade Strontium for AA and ICP 1000 ug/mL (1000 PPM) 500mL in 2% HCl |
|||
PLSR1-2X | Scientific Laboratory Supplies | 500ML | EUR 158.4 |
Genistein 10mM |
|||
TG4160 | TopoGen | 0.25ml | EUR 187.2 |
Assurance Grade Strontium for AA and ICP 1000 ug/mL (1000 PPM) 30mL in 2% HNO3 |
|||
PLSR2-2M | Scientific Laboratory Supplies | 30ML | EUR 34.8 |
Assurance Grade Strontium for AA and ICP 1000 ug/mL (1000 PPM) 250mL in 2% HNO3 |
|||
PLSR2-2T | Scientific Laboratory Supplies | 250ML | EUR 111.6 |
Assurance Grade Strontium for AA and ICP 1000 ug/mL (1000 PPM) 500mL in 2% HNO3 |
|||
PLSR2-2X | Scientific Laboratory Supplies | 500ML | EUR 144 |
Assurance Grade Strontium for AA and ICP 1000 ug/mL (1000 PPM) 125mL in 2% HNO3 |
|||
PLSR2-2Y01 | Scientific Laboratory Supplies | 125ML | EUR 64.8 |
Assurance Grade Strontium for AA and ICP 10000 ug/mL (10000 PPM) 500mL in 5% HNO3 |
|||
PLSR2-3X | Scientific Laboratory Supplies | 500ML | EUR 255.6 |
Assurance Grade Strontium for AA and ICP 10000 ug/mL (10000 PPM) 125mL in 5% HNO3 |
|||
PLSR2-3Y | Scientific Laboratory Supplies | 125ML | EUR 108 |
Strontium Chloride Diluting Solution |
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SRCL201 | Scientific Laboratory Supplies | 1L | EUR 72 |
Kinesis Hollow Cathode Lamp Strontium 37mm Std |
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CHR6011 | Scientific Laboratory Supplies | EACH | EUR 334.23 |
Claritas PPT Grade Strontium for ICP-MS 1 ug/mL (1 PPM) 125mL in 2% HNO3 |
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CLSR2-1BY | Scientific Laboratory Supplies | 125ML | EUR 103.2 |
Strontium chloride hexahydrate, 99%, ACS grade |
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GX3549-500G | Glentham Life Sciences | 500 g | EUR 122.4 |
Strontium Pieces max. 20 mm, under argon, coated with oil, Ba max. 1%, 99% |
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GX0588-100 | Glentham Life Sciences | 100 | EUR 550.7 |
Strontium chloride hexahydrate, 99%, ACS grade |
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GX3549-500 | Glentham Life Sciences | 500 | EUR 71.1 |
Kinesis Hollow Cathode Lamp Strontium 37mm unicam |
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CHR6015 | Scientific Laboratory Supplies | EACH | EUR 385.15 |
Kinesis Hollow Cathode Lamp Strontium 37mm Varian |
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CHR6017 | Scientific Laboratory Supplies | EACH | EUR 385.15 |
Genistein 8-c-glucoside |
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HY-N6882 | MedChemExpress | 10mM/1mL | EUR 1182 |
Kinesis Hollow Cathode Lamp Strontium 50mm Standard |
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CHR6019 | Scientific Laboratory Supplies | EACH | EUR 412.57 |
Kinesis Hollow Cathode Lamp Strontium 50mm PE AAnalyst (Lumina) |
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CHR6021 | Scientific Laboratory Supplies | EACH | EUR 539.21 |
Genistein (Tyrosine kinase inhibitor) |
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SIH-446-10MG | Stressmarq | 10 mg | EUR 117.6 |
Description: The substance Genistein is a tyrosine kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is creamy off-white solid which is soluble in DMSO (30 mg/ml), 100% ethanol (4 mg/ml) or dilute aqueous base; insoluble in water. |
Genistein (Tyrosine kinase inhibitor) |
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SIH-446-50MG | Stressmarq | 50 mg | EUR 198 |
Description: The substance Genistein is a tyrosine kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is creamy off-white solid which is soluble in DMSO (30 mg/ml), 100% ethanol (4 mg/ml) or dilute aqueous base; insoluble in water. |
Genistein 7,4'-di-O-β-D-glucopyranoside |
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TBW00747 | ChemNorm | 10mg | EUR 631.2 |
Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] |
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TBW00759 | ChemNorm | 10mg | EUR 886.8 |
4''-methyloxy-Genistin |
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HY-N4129 | MedChemExpress | 5mg | EUR 531.6 |
4''-methyloxy-Genistin |
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TBZ2680 | ChemNorm | 5mg | Ask for price |
Anti-Hu STRO-1 PE |
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1P-649-C025 | ExBio | 0.025 mg | EUR 168 |
Anti-Hu STRO-1 PE |
|||
1P-649-C100 | ExBio | 0.1 mg | EUR 288 |
Anti-Hu STRO-1 APC |
|||
1A-649-C025 | ExBio | 0.025 mg | EUR 168 |
Anti-Hu STRO-1 APC |
|||
1A-649-C100 | ExBio | 0.1 mg | EUR 288 |
STRO-1 Antibody |
|||
abx140247-01mg | Abbexa | 0.1 mg | EUR 610.8 |
STRO-1 Antibody (PE) |
|||
abx140285-01mg | Abbexa | 0.1 mg | EUR 577.2 |
STRO-1 Antibody (APC) |
|||
abx140284-01mg | Abbexa | 0.1 mg | EUR 577.2 |
Anti-Hu STRO-1 Purified |
|||
11-649-C025 | ExBio | 0.025 mg | EUR 178.8 |
Anti-Hu STRO-1 Purified |
|||
11-649-C100 | ExBio | 0.1 mg | EUR 309.6 |