Evaluation of Laboratory Application of Camelid Sera Containing Heavy-Chain Polyclonal Antibody

Laura April 26, 2021 0 Comments
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Evaluation of Laboratory Application of Camelid Sera Containing Heavy-Chain Polyclonal Antibody Against Recombinant CTLA-4 Protein. Cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) is a critical negative immunomodulatory receptor that is normally expressed in activated T cells and noticeably, in many cancerous cells. Indeed, molecular detection of CTLA-4 protein is crucial in basic research. In this work, the extracellular domain of the […]

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Efficient detection of eukaryotic calcium-sensing receptor

Laura April 26, 2021 0 Comments
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In direction of middle-up evaluation of polyclonal antibodies: subclass-specific N-glycosylation profiling of murine immunoglobulin G (IgG) by the use of HPLC-MS   Lately, superior HPLC-MS methods based mostly on intact protein (“top-down”) or protein subunit (“middle-up/middle-down”) evaluation have been applied for the characterization of therapeutic monoclonal antibodies. Right here, we assess feasibility of middle-up/middle-down evaluation for polyclonal […]

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In utero exposure to endogenous maternal polyclonal anti-Caspr2 antibody

Laura April 26, 2021 0 Comments
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Preparation and Characterization of Two Immunogens and Manufacturing of Polyclonal Antibody with Excessive Affinity and Specificity for Darunavir Darunavir (DRV) is a potent antiviral drug used for therapy of infections with human immunodeficiency virus (HIV). Efficient and protected therapy with DRV requires its therapeutic drug monitoring (TDM) in affected person’s plasma throughout remedy. To assist TDM of DRV, […]

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Preparation of a highly specific polyclonal antibody against and its use in development of ELISA

Laura April 26, 2021 0 Comments
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The prokaryotic expression, polyclonal antibody preparation, and subcellular localization of the transmembrane protein NS2A of the duck Tembusu virus   Duck Tembusu virus (DTMUV) is a single-stranded, positive-sense RNA arbovirus, belonging to the genus Flavivirus, household Flaviviridae. As a transmembrane protein, non-structural protein 2A (NS2A) performs an vital position in virion meeting, replication advanced and antagonizing host […]

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